ReviewPediatric surgery international2016
Pediatric lymphatic malformations: evolving understanding and therapeutic options.
Review in Pediatric surgery international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Multidimensional outcomes of initial treatment strategies for pediatric head and neck lymphatic malformations.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Masses of the fetal neck and oral cavity.Pediatric radiology · 2026Review
- In Utero Molecular-Targeted Drug Therapies: Translational Principles, Pharmacologic Considerations, and Emerging Clinical Applications.Journal of clinical medicine · 2026Review
- Article
- Impact of Intracystic Hemorrhage on Therapeutic Outcomes in Macro/Mixed Cystic Lymphatic Malformation: A Retrospective Cohort Study.Children (Basel, Switzerland) · 2025Article
- A real-world study of sirolimus in the treatment of pediatric head and neck lymphatic malformations.Journal of vascular surgery. Venous and lymphatic disorders · 2025Article
- A 14-year single-center experience evaluating sclerotherapy efficacy in lymphatic malformations.Journal of vascular surgery. Venous and lymphatic disorders · 2024Article
- Pediatric mediastinal lymphatic malformation: misdiagnosis analysis and literature review.BMC pediatrics · 2024Review
- Congenital Vascular Malformations in Children: From Historical Perspective to a Multidisciplinary Approach in the Modern Era-A Comprehensive Review.Children (Basel, Switzerland) · 2024Review
- Laparoscopic-assisted sclerotherapy in pediatric retroperitoneal lymphatic malformations.Frontiers in pediatrics · 2024Article
- Comprehensive targeted next-generation sequencing in patients with slow-flow vascular malformations.Journal of human genetics · 2022Article
- Article
- A Radiologic Grading System for Assessing the Radiographic Outcome of Treatment in Lymphatic and Lymphatic-Venous Malformations of the Head and Neck.AJNR. American journal of neuroradiology · 2021Article
- Imaging of the fetal oral cavity, airway and neck.Pediatric radiology · 2021Review
- Lymphatic malformations in children: treatment outcomes of sclerotherapy in a large cohort.European journal of pediatrics · 2021Article
- Combined endolymphatic and surgical treatment of a leaking central conducting lymphatic malformation in a neonate.Radiology case reports · 2021Article
- Refractory Head and Neck Lymphatic Malformation in Infants Treated With Sirolimus: A Case Series.Frontiers in oncology · 2021Article
- Lymphatic malformations compromising the upper airway in children: ultrasound-guided intralesional focal sclerotherapy with bleomycin targeting culprit lesions.Pediatric surgery international · 2020Article
- Giant lymphatic malformation causing abdominal compartment syndrome in a neonate: a rare surgical emergency.Journal of surgical case reports · 2020Article
- The Role of Interventional Radiologists in the Treatment of Congenital Lymphatic Malformations.Seminars in interventional radiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multimodal treatment of lymphatic malformations continues to expand as new information about the biology and genetics of these lesions is discovered, along with knowledge gained from clinical practice. A patient-centered approach, ideally provided by a multidisciplinary medical and surgical team, should guide timing and modality of treatment. Current treatment options include observation, surgery, sclerotherapy, radiofrequency ablation, and laser therapy. New medical and surgical therapies are emerging, and include sildenafil, propranolol, sirolimus, and vascularized lymph node transfer. The primary focus of management is to support and optimize these patients' quality of life. Researchers continue to study lymphatic malformations with the goal of increasing therapeutic options and developing effective clinical pathways for these complicated lesions.
Indexed as
Identifiers
26815877What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.