ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2009
Base excess determined within one hour of admission predicts mortality in patients with severe pelvic fractures and severe hemorrhagic shock.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Early Sex Differences in pH, Base Excess and Lactate for the Prediction of Mortality in Trauma Patients.Bioengineering (Basel, Switzerland) · 2026Article
- Unstable pelvic fractures in patients with hemodynamic instability: global treatment controversies.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Change in resuscitation influenced development and severity of inflammatory complications in severely injured.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Early correction of base deficit decreases late mortality in polytrauma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Effect of C-Clamp Application on Hemodynamic Instability in Polytrauma Victims with Pelvic Fracture.Medicina (Kaunas, Lithuania) · 2022Article
- Methylene Blue to Neonatal Septic Shock treatment in neonate pigsClinics (Sao Paulo, Brazil) · 2022Article
- Comparison of base excess, lactate and pH predicting 72-h mortality of multiple trauma.BMC emergency medicine · 2021Article
- The influence of alcohol on the outcome of trauma patients: a matched-pair analysis of the TraumaRegister DGUEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Article
- Article
- Focus on: Diagnostic and prognosis of severely traumatized patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2009Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnstable pelvic ring fractures with exsanguinating hemorrhages are rare but potentially lifethreatening injuries. The aim of this retrospective study was to evaluate whether early changes in acid- base parameters predict mortality of patients with severe pelvic trauma and hemorrhagic shock.
methodsData for 50 patients with pelvic ring disruption and severe hemorrhage were analyzed retrospectively. In all patients, the pelvic ring was temporarily stabilized by C-clamp. Patients with ongoing bleeding underwent laparotomy with extra and/or intraperitoneal pelvic packing, as required. Base excess, lactate, and pH were measured upon admission and at 1, 2, 3, 4, 6, 8, and 12 h postadmission. Patients were categorized as early survivors (surviving the first 12 h after admission) and nonsurvivors. Statistical analysis was performed by Mann-Whitney test; significance was assumed at p < 0.05. Receiver operating characteristic curves were generated for early mortality from each acid-base variable.
resultsSixteen patients (32%) were nonsurvivors due to hemorrhagic shock (n = 13) or severe traumatic brain injury (n = 3). Thirty-four patients were early survivors. Base excess, lactate, and pH significantly discriminated between early survivors and nonsurvivors. Base excess determined 1 h after admission discriminated most strongly, with an area under the receiver operating characteristic curve of 0.915 (95% confidence interval, 0.836-0.993; p < 0.001).
conclusionBase excess, lactate, and pH discriminate early survivors from nonsurvivors suffering from severe pelvic trauma and hemorrhagic shock. Base excess measured 1 h after admission best predicted early mortality following pelvic trauma with concomitant hemorrhage.
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