Evidence map›Paper›PMID 26815171›Full record

ReviewDigestive diseases and sciences2016

Nonalcoholic Fatty Liver Disease: Key Considerations Before and After Liver Transplantation.

Yuval A Patel, Carl L Berg, Cynthia A Moylan

Open access · greenAbstract readReview
In one paragraph

Review in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Holistic Approach in the Management of Nonalcoholic Fatty Liver Disease.Euroasian journal of hepato-gastroenterology · 2022
    Review
  6. Review
  7. Review
  8. Article
  9. Liver transplantation and aging.World journal of transplantation · 2020
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Observational
  16. Review
  17. Review
  18. Bariatric Surgery and Liver Transplantation.Gastroenterology & hepatology · 2017
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yuval A PatelDivision of Gastroenterology, Department of Medicine, Duke University School of Medicine, Duke University Medical Center, 905 South LaSalle Street, DUMC 3256, GSRB1, Durham, NC, 27710, USA.
Carl L BergDivision of Gastroenterology, Department of Medicine, Duke University School of Medicine, Duke University Medical Center, 905 South LaSalle Street, DUMC 3256, GSRB1, Durham, NC, 27710, USA.
Cynthia A MoylanDivision of Gastroenterology, Department of Medicine, Duke University School of Medicine, Duke University Medical Center, 905 South LaSalle Street, DUMC 3256, GSRB1, Durham, NC, 27710, USA. cynthia.moylan@duke.edu.ORCID http://orcid.org/0000-0001-8454-7086
Duke Medical Center · USDuke University · US

Funding

DUKE TRAINING GRANT IN DIGESTIVE DISEASES AND NUTRITIONT32DK007568 · NIDDK · DUKE UNIVERSITY · PI Katherine Garman, Rodger A. Liddle · 1988 to 2026
$5.6M
NIDDK NIH HHS T32 DK007568
6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is the most common etiology of chronic liver disease in developed countries and is on trajectory to become the leading indication for liver transplantation in the USA and much of the world. Patients with NAFLD cirrhosis awaiting liver transplant face unique challenges and increased risk for waiting list stagnation and dropout due to burdensome comorbidities including obesity, diabetes, cardiovascular disease, and kidney disease. Thus far, patients transplanted for NAFLD cirrhosis have excellent mid- and long-term patient and graft survival, but concerns regarding short-term morbidity and mortality continue to exist. Post-liver transplantation, NAFLD occurs as both a recurrent and de novo manifestation, each with unique outcomes. NAFLD in the donor population is of concern given the growing demand for liver transplantation and mounting pressure to expand the donor pool. This review addresses key issues surrounding NAFLD as an indication for transplantation, including its increasing prevalence, unique patient demographics, outcomes related to liver transplantation, development of post-liver transplantation NAFLD, and NAFLD in the liver donor population. It also highlights exciting areas where further research is needed, such as the role of bariatric surgery and preconditioning of marginal donor grafts.

Indexed as

Liver TransplantationEnd Stage Liver DiseaseHumansLiver CirrhosisNon-alcoholic Fatty Liver DiseaseRisk FactorsCirrhosisLiver transplantationNAFLDNASHObesityOutcomesReviewSteatosis

Identifiers

PMID26815171
PMCPMC5344743
OpenAlexW2289034598

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.