ArticleObesity (Silver Spring, Md.)2016
Subcutaneous fat mass in infancy and cardiovascular risk factors at school-age: The generation R study.
Article in Obesity (Silver Spring, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Infant fat mass and later child and adolescent health outcomes: a systematic review.Archives of disease in childhood · 2024Pooled it
- Can antenatal diet and lifestyle interventions influence childhood obesity? A systematic review.Maternal & child nutrition · 2018Pooled it
- Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy.International journal of obesity (2005) · 2017Trial
- Change in neighborhood socioeconomic status and childhood weight status and body composition from birth to adolescence.International journal of obesity (2005) · 2024Article
- Infant body composition: A comprehensive overview of assessment techniques, nutrition factors, and health outcomes.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023Review
- Maternal iron status in early pregnancy and childhood body fat measures and cardiometabolic risk factors: A population-based prospective cohort.The American journal of clinical nutrition · 2023Article
- Anthropometrics and fat mass, but not fat-free mass, are compromised in infants requiring parenteral nutrition after neonatal intestinal surgery.The American journal of clinical nutrition · 2022Article
- Prenatal exposure to ambient air pollutants and early infant growth and adiposity in the Southern California Mother's Milk Study.Environmental health : a global access science source · 2021Article
- Exclusivity of breastfeeding and body composition: learnings from the Baby-bod study.International breastfeeding journal · 2021Observational
- Subcutaneous fat mass in infancy and abdominal, pericardial and liver fat assessed by Magnetic Resonance Imaging at the age of 10 years.International journal of obesity (2005) · 2019Article
- Body composition during early infancy and its relation with body composition at 4 years of age in Jimma, an Ethiopian prospective cohort study.Nutrition & diabetes · 2018Article
- Associations of maternal obesity and excessive weight gain during pregnancy with subcutaneous fat mass in infancy.Early human development · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveTo examine the associations of infant subcutaneous fat with cardiovascular risk factors at school-age.
methodsIn a population-based prospective cohort study among 808 children, total subcutaneous fat (sum of biceps, triceps, suprailiacal, and subscapular skinfold thicknesses) and central-to-total subcutaneous fat ratio (sum of suprailiacal and subscapular skinfold thicknesses/total subcutaneous fat) at 1.5 and 24 months were estimated. At 6 years, body mass index, blood pressure, cholesterol, triglycerides, and insulin levels were measured.
resultsInfant subcutaneous fat measures were not associated with childhood blood pressure, triglycerides, or insulin levels. A 1-standard-deviation score (SDS) higher total subcutaneous fat at 1.5 months was, independently of body mass index, associated with lower low-density lipoprotein (LDL)-cholesterol levels at 6 years. In contrast, a 1-SDS higher total subcutaneous fat at 24 months was associated with higher total-cholesterol [difference 0.13 (95% confidence interval (CI) 0.03, 0.23) SDS] and LDL-cholesterol levels [difference 0.12 (95% CI 0.02, 0.21) SDS] at 6 years. There were no associations of central-to-total subcutaneous fat ratio with childhood cholesterol levels.
conclusionsThese results suggest that infant total subcutaneous fat is weakly associated with cholesterol levels at school-age. Further studies are needed to assess the long-term cardiometabolic consequences of infant body fat.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.