Evidence map›Paper›PMID 26812514›Full record

SynthesisThe journal of nutrition, health & aging2016

Effectiveness of Food-Based Fortification in Older People. A Systematic Review and Meta-Analysis.

J C Morilla-Herrera, F J Martín-Santos, J Caro-Bautista, C Saucedo-Figueredo, S García-Mayor, J M Morales-Asencio

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The journal of nutrition, health & aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  10. Recommending ultra-processed oral nutrition supplements for unintentional weight loss: Are there risks?Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J C Morilla-HerreraDr Jose Miguel Morales Asencio.C/ Arquitecto Francisco Peñalosa, 3. 29071 Malaga, Spain, jmmasen@uma.es.
F J Martín-Santos
J Caro-Bautista
C Saucedo-Figueredo
S García-Mayor
J M Morales-Asencio

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly intervention with nutritional support has been found to stop weight loss in older people malnourished or at risk of malnutrition. Enriched food could be a more attractive alternative to improve meals, than conventional oral nutritional supplements.

aimsTo determine the effectiveness of food-based fortification to prevent risk of malnutrition in elderly patients in community or institutionalized elderly patients.

methodsA systematic review was conducted of randomized controlled trials, quasi-experimental, and interrupted time series including a longitudinal analysis.

participantsElderly patients who are institutionalized, hospitalized or community-dwelling, with a minimum average age of 65 years. All type of patient groups, with the exception of people in critical care, or those who were recovering from cancer treatment, were included.

interventionStudies had to compare food-based fortification against alternatives. Studies that used oral nutritional supplementation such as commercial sip feeds, vitamin or mineral supplements were excluded. The search was conducted in Cochrane, CINAHL, PubMed, EMBASE, LILACS, and Cuiden. An independent peer review was carried out.

resultsFrom 1011 studies obtained, 7 were included for the systematic review, with 588 participants. It was possible to perform meta-analysis of four studies that provided results on caloric and protein intake. Food-based fortification yielded positive results in the total amount of ingested calories and protein. Nevertheless, due to the small number of participants and the poor quality of some studies, further high quality studies are required to provide reliable evidence. IMPLICATIONS FOR PRACTICE: Despite the limited evidence, due to their simplicity, low cost, and positive results in protein and calories intake, simple dietary interventions based on the food-based fortification or densification with protein or energy of the standard diet could be considered in patients at risk of malnutrition.

Indexed as

Energy IntakeFood, FortifiedHealth Services for the AgedAgedAged, 80 and overDietary ProteinsDietary SupplementsFemaleHumansMaleMalnutritionNutritional StatusDietary Proteins

Identifiers

PMID26812514
PMCPMC12877586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.