Evidence map›Paper›PMID 26812461›Full record

ArticleJournal of adolescent and young adult oncology2016

Perceptions, Attributions, and Emotions Toward Endocrine Therapy in Young Women with Breast Cancer.

Hayley E Walker, Shoshana M Rosenberg, Annette L Stanton, Keith J Petrie, Ann H Partridge

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of adolescent and young adult oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01468246 (Helping Ourselves, Helping Others), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01468246 active not recruitingnot on this map

Helping Ourselves, Helping Others: The Young Women's Breast Cancer Study

TypeobservationalSponsorDana-Farber Cancer InstituteRan2006 to 2035Enrolled1,302ConditionsBreast Cancer
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. Psychosocial issues and quality of life of parenting partners of young women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  18. Financial Impact of Breast Cancer in Black Versus White Women.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hayley E Walker1 Harvard Medical School , Boston, Massachusetts.
Shoshana M Rosenberg1 Harvard Medical School , Boston, Massachusetts.
Annette L Stanton3 Departments of Psychology and Psychiatry/Biobehavioral Sciences and Jonsson Comprehensive Cancer Center, University of California , Los Angeles, California.
Keith J Petrie4 The University of Auckland , Auckland, New Zealand .
Ann H Partridge1 Harvard Medical School , Boston, Massachusetts.

Funding

Harvard Education Program in Cancer Prevention Control (R25T)R25CA057711 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI DAVISON, KIRSTEN · 1992 to 2018
$8.5M
NCI NIH HHS NIH 5R25 CA057711
6 · The paper itself

Abstract

purposeThe aims of this study were to describe symptoms attributed to endocrine therapy (ET) and perceptions of ET in a sample of young women with breast cancer and to explore whether these factors are associated with adherence to ET.

methodsAn online questionnaire was completed by 106 young women taking ET for hormone receptor-positive breast cancer. In addition to demographic and medical characteristics, the survey assessed symptom attribution, emotions, and perceptions related to ET. A supplemental survey measuring adherence to ET was completed by 82/106 women. Means, medians, and frequency distributions were calculated for continuous and categorical covariates, respectively. An exploratory analysis evaluated whether adherence was associated with patient characteristics and views.

resultsThe mean age of respondents was 39 years (range 22-45 years). Two-thirds of women had stage 1 or 2 breast cancer. Women attributed an average of nine symptoms to ET; hot flashes, night sweats, and decreased libido were the most frequently attributed symptoms. Positive emotions toward ET were more common than negative emotions were, although only 48% of respondents believed that ET was essential. Women of higher financial status and those who reported more positive emotions toward ET reported greater adherence with ET. A significant difference in symptom attribution was not detected between less and more adherent respondents.

conclusionsYoung women's views regarding ET may play an important role in determining adherence behavior. Given that young women have a higher risk of recurrence, some of which may be attributable to ET non-adherence, further work is needed to confirm these findings and determine whether interventions designed to modify young women's perceptions of ET could promote adherence.

Indexed as

Health Knowledge, Attitudes, PracticeAdultAntineoplastic Agents, HormonalBreast NeoplasmsChemotherapy, AdjuvantDrug MonitoringEmotionsFemaleHot FlashesHumansLibidoMedication AdherenceMiddle AgedProspective StudiesRecurrenceSocioeconomic FactorsAntineoplastic Agents, Hormonalbreast cancerpsychosocialsurvivorship

Identifiers

PMID26812461
PMCPMC4779285

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.