Evidence map›Paper›PMID 26812078›Full record

ArticleVaccine2016

Provider communication and HPV vaccination: The impact of recommendation quality.

Melissa B Gilkey, William A Calo, Jennifer L Moss, Parth D Shah, Macary W Marciniak, Noel T Brewer

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Vaccine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05099497 (Big Data and Little Behaviours), which is not on this map. Cited by 289 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
289citing papers in PubMed, 7 pooled it
28.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05099497 nacompletednot on this mapstarted 2021, after this paper: background citation

Big Data and Little Behaviours: Feedback and Quality Improvement Supports to Primary Care to Facilitate COVID-19 Vaccine Uptake

TypeinterventionalSponsorWomen's College HospitalRan2021 to 2022Enrolled600ConditionsCovid19 Vaccination, Vaccine UptakeArmsUsing Practice Facilitators to Support Physicians
3 · Its place in the literature

Who cites it

289 citing papers in PubMed, 7 syntheses or guidelines pooled it, 418 citations in OpenAlex.

  1. Pooled it
  2. Identifying Healthcare Professionals With Lower Human Papillomavirus (HPV) Vaccine Recommendation Quality: A Systematic Review.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Disparities in Healthcare Providers' Recommendation of HPV Vaccination for U.S. Adolescents: A Systematic Review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. TeenVac.org: A Mobile Web App to Improve Human Papillomavirus Vaccine Uptake for Adolescent Boys.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Mechanisms of self-persuasion intervention for HPV vaccination: Testing memory and autonomous motivation.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021
    Trial
  15. Trial
  16. Trial
  17. Trial
  18. Article
  19. Article
  20. Article

229 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Melissa B GilkeyDepartment of Population Medicine, Harvard Medical School & Harvard Pilgrim Health Care Institute, 133 Brookline Ave., Boston, MA 02215, USA. Electronic address: gilkey@unc.edu.
William A CaloDepartment of Health Policy and Management, University of North Carolina, CB 7411, Chapel Hill, NC 27599, USA. Electronic address: wacalo@live.unc.edu.
Jennifer L MossDepartment of Health Behavior, University of North Carolina, CB 7440, Chapel Hill, NC 27599, USA. Electronic address: jlmoss@live.unc.edu.
Parth D ShahDepartment of Health Behavior, University of North Carolina, CB 7440, Chapel Hill, NC 27599, USA. Electronic address: pdshah@live.unc.edu.
Macary W MarciniakEshelman School of Pharmacy, University of North Carolina, CB 7355, Chapel Hill, NC 27599, USA. Electronic address: macary_marciniak@unc.edu.
Noel T BrewerDepartment of Health Behavior & Lineberger Comprehensive Cancer Center, University of North Carolina, CB 7440, Chapel Hill, NC 27599, USA. Electronic address: ntb@unc.edu.
University of North Carolina at Chapel Hill · USHarvard University · US

Funding

Cancer Training GrantR25CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BASCH, ETHAN M., REEVE, BRYCE B · 2008 to 2017
$4.0M
Cancer Control Education ProgramT32CA057726 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa B Gilkey, Melissa A. Troester · 2017 to 2026
$3.7M
Improving Healthcare Providers' Communication about HPV VaccineK22CA186979 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILKEY, MELISSA B · 2014 to 2016
$553k
Influence of yearly cycles in adolescent vaccination on cancer preventionF31CA189411 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOSS, JENNIFER LINDSAY · 2014 to 2014
$27k
NCI NIH HHS F31 CA189411NCI NIH HHS K22 CA186979NCI NIH HHS R25 CA116339NCI NIH HHS T32 CA057726
6 · The paper itself

Abstract

backgroundReceiving a healthcare provider's recommendation is a strong predictor of HPV vaccination, but little is known empirically about which types of recommendation are most influential. Thus, we sought to investigate the relationship between recommendation quality and HPV vaccination among U.S. adolescents.

methodsIn 2014, we conducted a national, online survey of 1495 parents of 11-17-year-old adolescents. Parents reported whether providers endorsed HPV vaccination strongly, encouraged same-day vaccination, and discussed cancer prevention. Using an index of these quality indicators, we categorized parents as having received no, low-quality, or high-quality recommendations for HPV vaccination. Separate multivariable logistic regression models assessed associations between recommendation quality and HPV vaccine initiation (≥ 1 dose), follow through (3 doses, among initiators), refusal, and delay.

resultsAlmost half (48%) of parents reported no provider recommendation for HPV vaccination, while 16% received low-quality recommendations and 36% received high-quality recommendations. Compared to no recommendation, high-quality recommendations were associated with over nine times the odds of HPV vaccine initiation (23% vs. 74%, OR=9.31, 95% CI, 7.10-12.22) and over three times the odds of follow through (17% vs. 44%, OR=3.82, 95% CI, 2.39-6.11). Low-quality recommendations were more modestly associated with initiation (OR=4.13, 95% CI, 2.99-5.70), but not follow through. Parents who received high- versus low-quality recommendations less often reported HPV vaccine refusal or delay.

conclusionsHigh-quality recommendations were strongly associated with HPV vaccination behavior, but only about one-third of parents received them. Interventions are needed to improve not only whether, but how providers recommend HPV vaccination for adolescents.

Indexed as

CommunicationPhysician-Patient RelationsAdolescentChildFemaleHealth Care SurveysHealth Knowledge, Attitudes, PracticeHumansLogistic ModelsMaleMultivariate AnalysisPapillomavirus InfectionsPapillomavirus VaccinesParentsPatient Acceptance of Health CareVaccinationPapillomavirus VaccinesAdolescent healthHealth communicationHuman papillomavirus infections/prevention and controlHuman papillomavirus vaccineQuality of health care

Identifiers

PMID26812078
PMCPMC4944755
OpenAlexW2256672782

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.