Evidence map›Paper›PMID 26812008›Full record

ArticleActa tropica2016

Seasonal dynamics and microgeographical spatial heterogeneity of malaria along the China-Myanmar border.

Yue Hu, Guofa Zhou, Yonghua Ruan, Ming-Chieh Lee, Xin Xu, Shuang Deng, Yao Bai, Jie Zhang, James Morris, Huaie Liu and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta tropica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Polymorphism of Antifolate Drug Resistance inFrontiers in cellular and infection microbiology · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Malaria in China, 2011-2015: an observational study.Bulletin of the World Health Organization · 2017
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yue Hu *Department of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Guofa Zhou *Program in Public Health, University of California at Irvine, Irvine, CA, USA.
Yonghua Ruan *Department of Pathology, Kunming Medical University, Kunming, China.
Ming-Chieh LeeProgram in Public Health, University of California at Irvine, Irvine, CA, USA.
Xin XuDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Shuang DengDepartment of Pathology, Kunming Medical University, Kunming, China.
Yao BaiDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Jie ZhangDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
James MorrisEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson University, SC, USA.
Huaie LiuDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Ying WangInstitute of Tropical Medicine, Third Military Medical University, Chongqing, China.
Qi FanDalian Institute of Biotechnology, Dalian, Liaoning, China.
Peipei LiDalian Institute of Biotechnology, Dalian, Liaoning, China.
Yanrui WuDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Zhaoqing YangDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Guiyun YanProgram in Public Health, University of California at Irvine, Irvine, CA, USA.
Liwang CuiDepartment of Entomology, The Pennsylvania State University, University Park, PA 16802, USA.

Funding

Southeast Asia Malaria Research CenterU19AI089672 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2010 to 2023
$28.9M
NIAID NIH HHS U19 AI089672
6 · The paper itself

Abstract

Malaria transmission is heterogeneous in the Greater Mekong Subregion with most of the cases occurring along international borders. Knowledge of transmission hotspots is essential for targeted malaria control and elimination in this region. This study aimed to determine the dynamics of malaria transmission and possible existence of transmission hotspots on a microgeographical scale along the China-Myanmar border. Microscopically confirmed clinical malaria cases were recorded in five border villages through a recently established surveillance system between January 2011 and December 2014. A total of 424 clinical cases with confirmed spatial and temporal information were analyzed, of which 330 (77.8%) were Plasmodium vivax and 88 (20.8%) were Plasmodium falciparum, respectively. The P. vivax and P. falciparum case ratio increased dramatically from 2.2 in 2011 to 4.7 in 2014, demonstrating that P. vivax malaria has become the predominant parasite species. Clinical infections showed a strong bimodal seasonality. There were significant differences in monthly average incidence rates among the study villages with rates in a village in China being 3-8 folds lower than those in nearby villages in Myanmar. Spatial analysis revealed the presence of clinical malaria hotspots in four villages. This information on malaria seasonal dynamics and transmission hotspots should be harnessed for planning targeted control.

Indexed as

ChinaGeographyHumansIncidenceMalariaMyanmarSeasonsChina–Myanmar borderClinical malariaHotspotSeasonality

Identifiers

PMID26812008
PMCPMC4779690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.