ArticleIranian journal of parasitology
Efficacy of the Bunium persicum (Boiss) Essential Oil against Acute Toxoplasmosis in Mice Model.
Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- Deciphering the biosynthesis pathway of gamma terpinene cuminaldehyde and para cymene in the fruit of Bunium persicum.Scientific reports · 2025Article
- Potent In Vitro and In Vivo Effects ofTropical medicine and infectious disease · 2023Article
- The role ofFrontiers in cellular and infection microbiology · 2023Article
- Tandem mass tag-based quantitative proteomics analyses of a chicken-original virulent and its attenuatedFrontiers in veterinary science · 2023Article
- Potential effects of alpha-pinene, a monoterpene commonly found in essential oils againstJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Nano amphotericin B: a good anti-leishmanial drug with effect on cathelicidin gene expression.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- Cytotoxic and Antileishmanial Effects of Various Extracts ofTurkish journal of pharmaceutical sciences · 2021Article
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- In vitro and in vivoFood science & nutrition · 2021Article
- Evaluation ofFrontiers in cellular and infection microbiology · 2021Article
- Prophylactic effects of biogenic selenium nanoparticles on acute toxoplasmosis: An in vivo study.Annals of medicine and surgery (2012) · 2020Article
- Efficacy and Safety Curcuma zadoaria L. to Inactivate the Hydatid Cyst Protoscoleces.Current clinical pharmacology · 2020Article
- Anticonvulsant Essential Oils and Their Relationship with Oxidative Stress in Epilepsy.Biomolecules · 2019Review
- Efficacy and safety of Curcuma longa essential oil to inactivate hydatid cyst protoscoleces.BMC complementary and alternative medicine · 2019Article
- Article
- A review on inactivation methods of Toxoplasma gondii in foods.Pathogens and global health · 2018Review
- Article
- Article
- Efficacy and Safety ofIranian journal of parasitologyArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe evaluated the in vivo activity of Bunium persicum (Boiss) essential oil on infected mice with acute toxoplasmosis.
methodsTo evaluate prophylactic effects, male NMRI mice received B. persicum essential oil at the concentrations of 0.05 and 0.1 mL/kg for 14 days. After 24 h mice were infected intraperitonealy with 1×10(4) tachyzoites of T. gondii, RH strain. In order to investigate therapeutic effects, mice were infected and then received B. persicum oil at the concentrations of 0.05 and 0.1 ml/kg two times a day for 5 days. The time/mean time of death in all infected mice and the number of tachyzoites from infected mice were recorded.
resultsThe time/mean time of death of infected mice was 8 and 9 days after oral administration of B. persicum oil at the concentration of 0.05 and 0.1 mL/kg, respectively (P<0.05). In contrast, the time/mean time of death control group was 5 days. In addition, B. persicum significantly reduced the mean number of tachyzoites compared with control group. The time/mean time of death of infected mice was 6 and 7 days after oral administration of B. persicum essential oil at the concentration of 0.05 and 0.1 mL/kg, respectively. In contrast, the time/mean time of death control group was 5 days. B. persicum especially at the concentration of 0.1 ml/kg significantly reduced the mean number of tachyzoites compared with control group.
conclusionThe results showed the potential of B. persicum essential oil as a natural source for the production of new prophylactic agent for use in toxoplasmosis.
Indexed as
Identifiers
26811730PMC4724840W2221890562What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.