Evidence map›Paper›PMID 26811667›Full record

ReviewWorld journal of gastroenterology2016

Antibody markers in the diagnosis of inflammatory bowel disease.

Keiichi Mitsuyama, Mikio Niwa, Hidetoshi Takedatsu, Hiroshi Yamasaki, Kotaro Kuwaki, Shinichiro Yoshioka, Ryosuke Yamauchi, Shuhei Fukunaga, Takuji Torimura

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 3 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 3 syntheses or guidelines pooled it, 147 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. ACG Clinical Guideline: Management of Crohn's Disease in Adults.The American journal of gastroenterology · 2018
    Guideline
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Divergent T Cell Phenotypes Define Pediatric Crohn's Disease and Ulcerative Colitis.medRxiv : the preprint server for health sciences · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Keiichi MitsuyamaKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Mikio NiwaKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Hidetoshi TakedatsuKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Hiroshi YamasakiKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Kotaro KuwakiKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Shinichiro YoshiokaKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Ryosuke YamauchiKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Shuhei FukunagaKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Takuji TorimuraKeiichi Mitsuyama, Inflammatory Bowel Disease Center, Kurume University School of Medicine, Kurume 830-0011, Japan.
Kurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a chronic intestinal inflammation of unknown etiology. The diagnosis of IBD is based on endoscopic, radiologic and histopathologic criteria. Recently, the search for a noninvasive marker that could augment or replace part of this diagnostic process has become a focus of IBD research. In this review, antibody markers, including microbial antibodies, autoantibodies and peptide antibodies, will be described, focusing on their common features. At present, no single marker with qualities that are satisfactory for the diagnosis and treatment of IBD has been identified, although panels of some antibodies are being evaluated with keen interest. The discovery of novel IBD-specific and sensitive markers is anticipated. Such markers could minimize the use of endoscopic and radiologic examinations and could enable clinicians to implement individualized treatment plans designed to improve the long-term prognosis of patients with IBD.

Indexed as

Serologic TestsAntibodiesAntibodies, BacterialAutoantibodiesBiomarkersColitis, UlcerativeCrohn DiseaseHumansPredictive Value of TestsPrognosisAntibodiesAntibodies, BacterialAutoantibodiesBiomarkersBiomarkerCrohn’s diseaseSerological antibodyUlcerative colitis

Identifiers

PMID26811667
PMCPMC4716040
OpenAlexW2268687848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.