Evidence map›Paper›PMID 26811521›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2016

Financial Insolvency as a Risk Factor for Early Mortality Among Patients With Cancer.

Scott D Ramsey, Aasthaa Bansal, Catherine R Fedorenko, David K Blough, Karen A Overstreet, Veena Shankaran, Polly Newcomb

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 463 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
463citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06278831 completednot on this mapstarted 2023, after this paper: background citation

Efficacy of Structured SOcial COnsultation and Support in Reducing the FINancial Burden of Radiotherapy

TypeobservationalSponsorUniversity Medical Center GoettingenRan2023 to 2024Enrolled230ConditionsFinancial ToxicityArmsQuestionnaire
NCT06296641 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Leveraging COmmunity Partnered nEeds Navigation to Reduce Unmet Health-related Social Needs Among Caregivers for Adolescent and Younger Adult Cancer Survivors

TypeinterventionalSponsorColumbia UniversityRan2024 to 2026Enrolled60ConditionsCancer in AdolescenceArmsNeeds navigation intervention
3 · Its place in the literature

Who cites it

463 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Towards the assessment of financial distress among cancer patients: a conceptual model of the financial effects of a tumour disease.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  3. Evaluation of financial toxicity and associated factors in female patients with breast cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  4. Pooled it
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  7. Trial
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  11. Financial hardship experience in middle- and older-aged patients with advanced lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  12. Trial
  13. A proactive financial navigation intervention in patients with newly diagnosed gastric and gastroesophageal junction adenocarcinoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  14. Financial Toxicity Monitoring in a Randomized Controlled Trial of Patient-Reported Outcomes During Cancer Treatment (Alliance AFT-39).Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Trial
  15. Trial
  16. Assessing financial toxicity with COST-FACIT: experience from a tertiary care cancer center.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  17. Article
  18. Article
  19. Beyond tumor response: hope and decision regret during immunotherapy for hepatocellular carcinoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  20. Article

403 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Scott D RamseyScott D. Ramsey, Aasthaa Bansal, Catherine R. Fedorenko, and Polly Newcomb, Fred Hutchinson Cancer Research Center; Aasthaa Bansal, University of Washington; Veena Shankaran, University of Washington School of Medicine; Karen A. Overstreet, US Bankruptcy Court, Western District of Washington, Seattle, WA; and David K. Blough, Bechtel, Schenectady, NY. sramsey@fredhutch.org.
Aasthaa BansalScott D. Ramsey, Aasthaa Bansal, Catherine R. Fedorenko, and Polly Newcomb, Fred Hutchinson Cancer Research Center; Aasthaa Bansal, University of Washington; Veena Shankaran, University of Washington School of Medicine; Karen A. Overstreet, US Bankruptcy Court, Western District of Washington, Seattle, WA; and David K. Blough, Bechtel, Schenectady, NY.
Catherine R FedorenkoScott D. Ramsey, Aasthaa Bansal, Catherine R. Fedorenko, and Polly Newcomb, Fred Hutchinson Cancer Research Center; Aasthaa Bansal, University of Washington; Veena Shankaran, University of Washington School of Medicine; Karen A. Overstreet, US Bankruptcy Court, Western District of Washington, Seattle, WA; and David K. Blough, Bechtel, Schenectady, NY.
David K BloughScott D. Ramsey, Aasthaa Bansal, Catherine R. Fedorenko, and Polly Newcomb, Fred Hutchinson Cancer Research Center; Aasthaa Bansal, University of Washington; Veena Shankaran, University of Washington School of Medicine; Karen A. Overstreet, US Bankruptcy Court, Western District of Washington, Seattle, WA; and David K. Blough, Bechtel, Schenectady, NY.
Karen A OverstreetScott D. Ramsey, Aasthaa Bansal, Catherine R. Fedorenko, and Polly Newcomb, Fred Hutchinson Cancer Research Center; Aasthaa Bansal, University of Washington; Veena Shankaran, University of Washington School of Medicine; Karen A. Overstreet, US Bankruptcy Court, Western District of Washington, Seattle, WA; and David K. Blough, Bechtel, Schenectady, NY.
Veena ShankaranScott D. Ramsey, Aasthaa Bansal, Catherine R. Fedorenko, and Polly Newcomb, Fred Hutchinson Cancer Research Center; Aasthaa Bansal, University of Washington; Veena Shankaran, University of Washington School of Medicine; Karen A. Overstreet, US Bankruptcy Court, Western District of Washington, Seattle, WA; and David K. Blough, Bechtel, Schenectady, NY.
Polly NewcombScott D. Ramsey, Aasthaa Bansal, Catherine R. Fedorenko, and Polly Newcomb, Fred Hutchinson Cancer Research Center; Aasthaa Bansal, University of Washington; Veena Shankaran, University of Washington School of Medicine; Karen A. Overstreet, US Bankruptcy Court, Western District of Washington, Seattle, WA; and David K. Blough, Bechtel, Schenectady, NY.

Funding

Training and Research in Colon Cancer SurvivalK05CA152715 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI NEWCOMB, POLLY A · 2010 to 2019
$991k
CCR NIH HHS RC1004135NCI NIH HHS K05 CA152715
6 · The paper itself

Abstract

purposePatients with cancer are more likely to file for bankruptcy than the general population, but the impact of severe financial distress on health outcomes among patients with cancer is not known.

methodsWe linked Western Washington SEER Cancer Registry records with federal bankruptcy records for the region. By using propensity score matching to account for differences in several demographic and clinical factors between patients who did and did not file for bankruptcy, we then fit Cox proportional hazards models to examine the relationship between bankruptcy filing and survival.

resultsBetween 1995 and 2009, 231,596 persons were diagnosed with cancer. Patients who filed for bankruptcy (n = 4,728) were more likely to be younger, female, and nonwhite, to have local- or regional- (v distant-) stage disease at diagnosis, and have received treatment. After propensity score matching, 3,841 patients remained in each group (bankruptcy v no bankruptcy). In the matched sample, mean age was 53.0 years, 54% were men, mean income was $49,000, and majorities were white (86%), married (60%), and urban (91%) and had local- or regional-stage disease at diagnosis (84%). Both groups received similar initial treatments. The adjusted hazard ratio for mortality among patients with cancer who filed for bankruptcy versus those who did not was 1.79 (95% CI, 1.64 to 1.96). Hazard ratios varied by cancer type: colorectal, prostate, and thyroid cancers had the highest hazard ratios. Excluding patients with distant-stage disease from the models did not have an effect on results.

conclusionSevere financial distress requiring bankruptcy protection after cancer diagnosis appears to be a risk factor for mortality. Further research is needed to understand the process by which extreme financial distress influences survival after cancer diagnosis and to find strategies that could mitigate this risk.

Indexed as

BankruptcyFemaleHumansMaleMiddle AgedNeoplasmsProportional Hazards ModelsRisk FactorsSEER ProgramStress, PsychologicalWashington

Identifiers

PMID26811521
PMCPMC4933128

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.