Evidence map›Paper›PMID 26811484›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2016

Mitochondria, complexity, and evolutionary deficit spending.

Nick Lane, William F Martin

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Demand-only energetics at 120 ATP per glucose: A reply to Lynch.Biochimica et biophysica acta. Bioenergetics · 2026
    Article
  2. The archaeal roots of eukaryotic life.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Eukaryogenesis From FECA to LECA: Radical Steps Along the Way.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  4. Review
  5. The exceptional form and function of the giant bacteriumProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Powerhouses in the cold: mitochondrial function during thermal acclimation in montane mayflies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Farming the mitochondrial ancestor as a model of endosymbiotic establishment by natural selection.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  16. Article
  17. Lokiarchaeon is hydrogen dependent.Nature microbiology · 2016
    Article
  18. Reply to Lane and Martin: Mitochondria do not boost the bioenergetic capacity of eukaryotic cells.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nick LaneDepartment of Genetics, Evolution and Environment, University College London, London WC1E 6BT, United Kingdom; nick.lane@ucl.ac.uk.
William F MartinInstitute of Molecular Evolution, Heinrich Heine University, 40225 Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Energy MetabolismEvolution, MolecularModels, BiologicalAnimalsEukaryotic CellsGenomeHumansProkaryotic Cells

Identifiers

PMID26811484
PMCPMC4760804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.