Evidence map›Paper›PMID 26811162›Full record

SynthesisJournal of the American Heart Association2016

Radial Artery Occlusion After Transradial Interventions: A Systematic Review and Meta-Analysis.

Muhammad Rashid, Chun Shing Kwok, Samir Pancholy, Sanjay Chugh, Sasko A Kedev, Ivo Bernat, Karim Ratib, Adrian Large, Doug Fraser, James Nolan and 1 more

5 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 167 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 8 pooled it
25.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04748068 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Use of Glidesheath Slender to Reduce Radial Artery Occlusion Following 7 French Transradial Coronary Intervention

TypeinterventionalSponsorChina National Center for Cardiovascular DiseasesRan2021 to 2021Enrolled500ConditionsRadial Artery Occlusion, Coronary Artery DiseaseArms7-Fr Glidesheath Slender, Cordis 7-Fr radial sheath
NCT04801901 nacompletednot on this mapstarted 2021, after this paper: background citation

PRESERVE Radial: A PRospEctive Randomized Clinical Study Comparing Radial ArtERy Intimal Hyperplasia Following Distal Vs. ForEarm TransRadial Arterial Access for Coronary Angiography

TypeinterventionalSponsorInova Health Care ServicesRan2021 to 2022Enrolled64ConditionsTransradial Access, Coronary Angiography, Radial Artery Intimal Medial Thickness, Distal Radial Artery Access (dTRA)ArmsdTRA, fTRA
NCT05253820 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparison of the Long-term Radial Artery Occlusion in Coronary Diagnosis and Intervention Via Distal vs Conventional Radial Approach: Randomized-controlled Trial(CONDITION)

TypeinterventionalSponsorWujin People's HospitalRan2022 to 2023Enrolled801ConditionsCoronary Artery Disease, Distal Radial Artery, Radial Artery OcclusionArmsdistal radial approach, conventional radial access
NCT07257367 recruitingnot on this mapstarted 2025, after this paper: background citation

Accuracy and Safety Assessment of Pressure Sensing Sheath Blood Pressure Monitoring Compared to Traditional Invasive and Non-invasive Blood Pressure Monitoring in Interventional Procedures: A Prospective, Single-Center, Self-Controlled Randomized Study

TypeobservationalSponsorShanghai Fourth People's Hospital Tongji UniversityRan2025 to 2027Enrolled50ConditionsBlood Pressure Monitoring, Neuroendovascular ProceduresArmsPressure Sensing Sheath Monitoring, Radial Arterial Line Monitoring
NCT07617259 narecruitingnot on this mapstarted 2026, after this paper: background citation

UltraSound Guided Distal Radial Artery vS Conventional Transradial Access for Interventional Coronary Angiography

TypeinterventionalSponsorUniversity Hospital of PatrasRan2026 to 2028Enrolled1,400ConditionsRadial Artery Access, Distal Radial Artery Access (dTRA)Armscoronary angiography
3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 8 syntheses or guidelines pooled it, 424 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Transradial Approach for Aortoiliac and Femoropopliteal Interventions: A Systematic Review and Meta-analysis.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2018
    Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Distal access and procedural anticoagulation to prevent radial artery occlusion after coronary angiography - the randomised RAPID trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Trial
  12. Trial
  13. Traditional Versus Distal Radial Access for Coronary Diagnostic and Revascularization Procedures: Final Results of the TENDERA Multicenter, Randomized Controlled Study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2024
    Trial
  14. Trial
  15. Incidence and predictors of radial artery occlusion following transradial coronary angiography: the proRadial trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2023
    Trial
  16. Comparison of Radifocus versus Silverway Guidewires for Percutaneous Radial Angiography Following Failed Use of a J-Tip Guidewire.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Trial
  17. Study on the Safety of the New Radial Artery Hemostasis Device.Journal of interventional cardiology · 2022
    Trial
  18. Trial
  19. Radial artery dilatation to improve access and lower complications during coronary angiography: the RADIAL trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021
    Trial
  20. Trial

107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 4 countries.

Muhammad RashidSt. Helens & Knowsley Teaching Hospital (NHS) Trust, Whiston Hospital, Prescot, UK (M.R.) Keele Cardiovascular Research Group, University of Keele, Stoke-on-Trent, UK (M.R., C.S.K., M.A.M.).
Chun Shing KwokKeele Cardiovascular Research Group, University of Keele, Stoke-on-Trent, UK (M.R., C.S.K., M.A.M.).
Samir PancholyThe Wright Center for Graduate Medical Education, The Commonwealth Medical College, Scranton, PA (S.P.).
Sanjay ChughArtemis Hospital, Gurgaon, India (S.C.).
Sasko A KedevUniversity Clinic of Cardiology Skopje, Skopje, Macedonia (S.A.K.).
Ivo BernatUniversity Hospital and Faculty of Medicine Pilsen, Pilsen, Czech Republic (I.B.).
Karim RatibRoyal Stoke Hospital, University Hospital North Midlands Trust, Stoke-on-Trent, UK (K.R., A.L., J.N., M.A.M.).
Adrian LargeRoyal Stoke Hospital, University Hospital North Midlands Trust, Stoke-on-Trent, UK (K.R., A.L., J.N., M.A.M.).
Doug FraserManchester Heart Centre, Manchester Royal Infirmary, Manchester, UK (D.F.).
James NolanRoyal Stoke Hospital, University Hospital North Midlands Trust, Stoke-on-Trent, UK (K.R., A.L., J.N., M.A.M.).
Mamas A MamasKeele Cardiovascular Research Group, University of Keele, Stoke-on-Trent, UK (M.R., C.S.K., M.A.M.) Royal Stoke Hospital, University Hospital North Midlands Trust, Stoke-on-Trent, UK (K.R., A.L., J.N., M.A.M.) Farr Institute, Institute of Population Health, University of Manchester, UK (M.A.M.).
Royal Stoke University Hospital · GBKeele University · GBArtemis Hospitals · INFarr Institute · GBManchester Royal Infirmary · GBThe Wright Center for Graduate Medical Education · USUniversity Clinic of Traumatology · AT

Funding

Medical Research Council MC_PC_13042Medical Research Council MR/K006665/1
6 · The paper itself

Abstract

backgroundRadial artery occlusion (RAO) may occur posttransradial intervention and limits the radial artery as a future access site, thus precluding its use as an arterial conduit. In this study, we investigate the incidence and factors influencing the RAO in the current literature. METHODS AND

resultsWe searched MEDLINE and EMBASE for studies of RAO in transradial access. Relevant studies were identified and data were extracted. Data were synthesized by meta-analysis, quantitative pooling, graphical representation, or by narrative synthesis. A total of 66 studies with 31 345 participants were included in the analysis. Incident RAO ranged between <1% and 33% and varied with timing of assessment of radial artery patency (incidence of RAO within 24 hours was 7.7%, which decreased to 5.5% at >1 week follow-up). The most efficacious measure in reducing RAO was higher dose of heparin, because lower doses of heparin were associated with increased RAO (risk ratio 0.36, 95% CI 0.17-0.76), whereas shorter compression times also reduced RAO (risk ratio 0.28, 95% CI 0.05-1.50). Several factors were found to be associated with RAO including age, sex, sheath size, and diameter of radial artery, but these factors were not consistent across all studies.

conclusionsRAO is a common complication of transradial access. Maintenance of radial patency should be an integral part of all procedures undertaken through the radial approach. High-dose heparin along with shorter compression times and patent hemostasis is recommended in reducing RAO.

Indexed as

VasoconstrictionAgedAnticoagulantsArterial Occlusive DiseasesCatheterization, PeripheralChi-Square DistributionDose-Response Relationship, DrugFemaleHeparinHumansIncidenceMaleMiddle AgedOdds RatioPuncturesRadial ArteryAnticoagulantsHeparinradial artery occlusiontransradial catheterization or accessvascular complications

Identifiers

PMID26811162
PMCPMC4859386
OpenAlexW2283167747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.