Evidence map›Paper›PMID 26810921›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2016

Ophthalmia neonatorum treatment and prophylaxis: IPOSC global study.

Ofira Zloto, Almutez Gharaibeh, Eedy Mezer, Branislav Stankovic, Sherwin Isenberg, Tamara Wygnanski-Jaffe

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Interventions for preventing ophthalmia neonatorum.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.Journal of the Pediatric Infectious Diseases Society · 2018
    Pooled it
  3. Article
  4. Article
  5. Relative frequencies of ophthalmia neonatorum and congenital nasolacrimal duct obstruction.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. A Survey of Current Prophylactic Treatment for Ophthalmia Neonatorum in Croatia and a Review of International Preventive Practices.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  10. The Growing Threat of Gonococcal Blindness.Antibiotics (Basel, Switzerland) · 2018
    Article
  11. Management of Extraocular Infections.Indian journal of pediatrics · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Ofira ZlotoDepartment of Ophthalmology, Sheba Medical Center, Goldschleger Eye Institute, Tel Hashomer, 52621, Israel.
Almutez GharaibehDepartment of Special Surgery-Ophthalmology, Faculty of Medicine, The University of Jordan, Amman, Jordan.
Eedy MezerDepartment of Ophthalmology, Rambam Health Care Campus, PO Box 9907, Haifa, 3109901, Israel.
Branislav StankovicClinical Center of Serbia, Institutes of Ophthalmology, Belgrade, Serbia.
Sherwin IsenbergJules Stein Eye Institute, University of California, Los Angeles, CA, USA.
Tamara Wygnanski-JaffeDepartment of Ophthalmology, Sheba Medical Center, Goldschleger Eye Institute, Tel Hashomer, 52621, Israel. twjaffe@hotmail.com.
Rambam Health Care Campus · ILSheba Medical Center · ILTel Aviv University · ILUniversity of California, Los Angeles · USUniversity of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCharacteristics of ophthalmia neonatorum (ON) amongst paediatric ophthalmologists remain unclear. The purpose of this current study is to examine the incidence, diagnosis, treatment, and prophylaxis of ON cases presenting to members of the American Association of Paediatric Ophthalmology and Strabismus (AAPOS).

methodsAn email containing a web link to a survey was sent to all members of AAPOS. The questionnaire examined the incidence of ON, etiology, diagnostic methods, treatment, and prophylaxis of the disease in different countries around the world.

resultsTwo hundred and ninety-one ophthalmologists answered the questionnaire. Most were from North America (52.94 %). One hundred and seventy-six (60.69 %) ophthalmologists encountered 0-5 cases of ON per year. The most common pathogens causing ON was Chlamydia trachomatis (35.37 %). Two hundred and forty-two (85.21 %) treat empirically when encountering ON during the first 10 days of life and 205 (75.09 %) after the first 10 days of life. In both cases, erythromycin was the most common first line of treatment. Two hundred and twenty-two (78.72 %) ophthalmologists replied that prophylactic treatment is required in their country. The most common agent for prophylaxis was erythromycin ointment (71.50 %).

conclusionsWe found that the incidence of ON per year per practitioner is 0-5 cases, the most common etiology is C. trachomatis, and most infants receive prophylaxis and treatment.

Indexed as

Antibiotic ProphylaxisAnti-Infective AgentsConjunctivitis, BacterialGlobal HealthHealth SurveysHumansIncidenceInfant, NewbornOphthalmia NeonatorumOphthalmologyPractice Patterns, Physicians'Societies, MedicalSurveys and QuestionnairesAnti-Infective AgentsAAPOSChlamydia trachomatisConjunctivitisIPOSCNeisseria gonorrhoeaeOphthalmia neonatorumProphylaxis

Identifiers

PMID26810921
OpenAlexW2299235748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.