Evidence map›Paper›PMID 26810763›Full record

ReviewJournal of plant research2016

Signaling mechanisms of plant cryptochromes in Arabidopsis thaliana.

Bobin Liu, Zhaohe Yang, Adam Gomez, Bin Liu, Chentao Lin, Yoshito Oka

Abstract readReview
In one paragraph

Review in Journal of plant research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
28.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Developing Optogenetic Approaches to Study CaCold Spring Harbor perspectives in biology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Sensing a rainbow of colors: algal photoreceptors.Frontiers in plant science · 2025
    Review
  8. Molecular mechanisms underlying the signal perception and transduction during seed germination.Molecular breeding : new strategies in plant improvement · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. A structural decryption of cryptochromes.Frontiers in chemistry · 2024
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bobin LiuBasic Forestry and Proteomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Zhaohe YangBasic Forestry and Proteomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Adam GomezMolecular, Cellular and Integrative Physiology, University of California, Los Angeles, CA, 90095, USA.
Bin LiuInstitute of Crop Sciences, Chinese Academy of Agriculture Sciences, Beijing, 100081, People's Republic of China.
Chentao LinDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, 90095, USA.
Yoshito OkaBasic Forestry and Proteomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China. YoshitoOka@fafu.edu.cn.
Fujian Agriculture and Forestry University · CNUniversity of California, Los Angeles · US

Funding

The signaling mechanisms of Arabidopsis CRY2R01GM056265 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LIN, CHENTAO · 2001 to 2021
$9.5M
NIGMS NIH HHS R01 GM056265
6 · The paper itself

Abstract

Cryptochromes (CRY) are flavoproteins that direct a diverse array of developmental processes in response to blue light in plants. Conformational changes in CRY are induced by the absorption of photons and result in the propagation of light signals to downstream components. In Arabidopsis, CRY1 and CRY2 serve both distinct and partially overlapping functions in regulating photomorphogenic responses and photoperiodic flowering. For example, both CRY1 and CRY2 regulate the abundance of transcription factors by directly reversing the activity of E3 ubiquitin ligase on CONSTITUTIVE PHOTOMORPHOGENIC 1 and SUPPRESSOR OF PHYA-105 1 complexes in a blue light-dependent manner. CRY2 also specifically governs a photoperiodic flowering mechanism by directly interacting with a transcription factor called CRYPTOCHROME-INTERACTING BASIC-HELIX-LOOP-HELIX. Recently, structure/function analysis of CRY1 revealed that the CONSTITUTIVE PHOTOMORPHOGENIC 1 independent pathway is also involved in CRY1-mediated inhibition of hypocotyl elongation. CRY1 and CRY2 thus not only share a common pathway but also relay light signals through distinct pathways, which may lead to altered developmental programs in plants.

Indexed as

Light Signal TransductionArabidopsisArabidopsis ProteinsCryptochromesGene Expression Regulation, PlantHypocotylLightPhosphorylationProtein DomainsTranscription FactorsArabidopsis ProteinsCRY1 protein, ArabidopsisCRY2 protein, ArabidopsisCryptochromesTranscription FactorsCryptochromeDe-etiolationFloweringPhotomorphogenesisTranscription

Identifiers

PMID26810763
PMCPMC6138873
OpenAlexW2263246619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.