Evidence map›Paper›PMID 26810594›Full record

ReviewCirculation. Arrhythmia and electrophysiology2016

Molecular Mechanisms of Sympathetic Remodeling and Arrhythmias.

Ryan T Gardner, Crystal M Ripplinger, Rachel C Myles, Beth A Habecker

Abstract readReview
In one paragraph

Review in Circulation. Arrhythmia and electrophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Acute arrhythmias in a long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency mouse model.American journal of physiology. Heart and circulatory physiology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Circadian rhythms in cardiovascular disease.European heart journal · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan T GardnerFrom the Department of Physiology and Pharmacology and Knight Cardiovascular Institute, Oregon Health and Science University, Portland (R.T.G., B.A.H.); Department of Pharmacology, School of Medicine, University of California, Davis (C.M.R.); and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom (R.C.M.).
Crystal M RipplingerFrom the Department of Physiology and Pharmacology and Knight Cardiovascular Institute, Oregon Health and Science University, Portland (R.T.G., B.A.H.); Department of Pharmacology, School of Medicine, University of California, Davis (C.M.R.); and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom (R.C.M.).
Rachel C MylesFrom the Department of Physiology and Pharmacology and Knight Cardiovascular Institute, Oregon Health and Science University, Portland (R.T.G., B.A.H.); Department of Pharmacology, School of Medicine, University of California, Davis (C.M.R.); and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom (R.C.M.).
Beth A HabeckerFrom the Department of Physiology and Pharmacology and Knight Cardiovascular Institute, Oregon Health and Science University, Portland (R.T.G., B.A.H.); Department of Pharmacology, School of Medicine, University of California, Davis (C.M.R.); and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom (R.C.M.). habecker@ohsu.edu.

Funding

Neurotrophins and post-infarct plasticity in cardiac sympathetic neuronsR01HL093056 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI BETH A HABECKER · 2009 to 2026
$7.9M
The Role of Adrenergic Stimulation in ArrhythmogenesisR01HL111600 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Crystal May Ripplinger · 2012 to 2026
$7.1M
Regulation of Sympathetic Function by InfarctionR01HL068231 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HABECKER, BETH A · 2001 to 2015
$4.3M
Training in Translational Science and Cardiovascular MedicineT32HL094294 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALKAYED, NABIL J · 2009 to 2018
$3.5M
British Heart FoundationNHLBI NIH HHS HL068231NHLBI NIH HHS HL093056NHLBI NIH HHS HL111600NHLBI NIH HHS R01 HL068231NHLBI NIH HHS R01 HL093056NHLBI NIH HHS R01 HL111600NHLBI NIH HHS T32 HL094294NHLBI NIH HHS T32HL094294Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heart RateNeuronal PlasticityAnimalsArrhythmias, CardiacHeartHumansMyocardiumNerve DegenerationNorepinephrineRisk FactorsSympathetic Nervous SystemNorepinephrineelectrophysiologymyocardial infarctionnorepinephrinereceptors, adrenergicsympathetic nervous system

Identifiers

PMID26810594
PMCPMC4730917

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.