SynthesisWorld journal of surgical oncology2016
Outcome of rectal cancer surgery in obese and nonobese patients: a meta-analysis.
Synthesis in World journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- The effect of excess body weight on short-term outcomes following minimally invasive rectal cancer surgery: a systematic review and meta-analysis.Techniques in coloproctology · 2026Pooled it
- Effect of obesity on perioperative outcomes following gastrointestinal surgery: meta-analysis.BJS open · 2023Pooled it
- Impact of obesity on morbidity and oncologic outcomes after total mesorectal excision for mid and low rectal cancer.Techniques in coloproctology · 2023Pooled it
- Effect of body mass index on surgical site wound infection, mortality, and postoperative hospital stay in subjects undergoing possibly curative surgery for colorectal cancer: A meta-analysis.International wound journal · 2023Pooled it
- Trial
- Prophylactic negative-pressure wound therapy after ileostomy reversal for the prevention of wound healing complications in colorectal cancer patients: a randomized controlled trial.Techniques in coloproctology · 2021Trial
- Development and validation of an interpretable machine learning model for predicting postoperative complications after transanal total mesorectal excision: a multicenter study.Techniques in coloproctology · 2026Article
- SAGES colorectal and metabolic bariatric surgery committee joint task force call to action for synchronized severe obesity and colorectal cancer management.Surgical endoscopy · 2026Review
- Short- and long-term outcomes of minimally invasive total mesorectal excision in obese versus nonobese patients with rectal cancer: a propensity score matched study.Techniques in coloproctology · 2026Article
- The Impact of Obesity on Operative Outcomes and Long-Term Oncological Outcomes Following Rectal Cancer Surgery: A Retrospective Single-Center Study.Journal of clinical medicine · 2026Article
- Predictive model of the surgical difficulty of robot-assisted total mesorectal excision for rectal cancer: a multicenter, retrospective study.Journal of robotic surgery · 2024Article
- Article
- Comparing short-term outcomes of robot-assisted and conventional laparoscopic total mesorectal excision surgery for rectal cancer in elderly patients.World journal of gastrointestinal surgery · 2024Article
- The impact of obesity on thyroidectomy outcomes: a case-matched study.Updates in surgery · 2024Article
- Interpretable machine learning model to predict surgical difficulty in laparoscopic resection for rectal cancer.Frontiers in oncology · 2024Review
- Prediction model construction for the occurrence of LARS after neoadjuvant therapy combined with laparoscopic total mesorectal excision in male patients with mid-low rectal cancer.Frontiers in oncology · 2024Article
- [Obesity and Colorectal Cancer].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Review
- Endoscopic management of anastomotic leakage after colorectal cancer surgery in a Moroccan center: A case series and literature review.SAGE open medical case reports · 2023Article
- Laparoscopic versus open resection for stage II/III rectal cancer in obese patients: A multicenter propensity score-based analysis of short- and long-term outcomes.Annals of gastroenterological surgery · 2023Article
- Factors Influencing the Difficulty and Need for External Help during Laparoscopic Appendectomy: Analysis of 485 Procedures from the Resident-1 Multicentre Trial.Journal of personalized medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe escalating global epidemic of obesity is of worldwide concern because of its association with serious negative effects on health. The technical difficulty of rectal cancer surgery is exacerbated in obese patients, which may compromise outcomes. High-quality, relevant evidence is limited. This meta-analysis aims to assess the outcomes of rectal cancer surgery in obese and nonobese patients.
methodsThe electronic databases Pubmed, Medline, Embase, Web of Science, and the Cochrane Library were used to search for articles that evaluated the outcomes of rectal cancer surgery in obese and nonobese patients. Fixed-effects and random-effects models were used to calculate the combined overall effect sizes of pooled data. Data are presented as odds ratios (OR) or weighted mean differences (WMD) with 95% confidence intervals (CIs).
resultsTen appropriate observational studies were identified from 290 published articles. In the obese group, conversion rates (OR 2.78; 95% CI 1.67-4.61), overall morbidity (OR 1.36; 95% CI 1.25-1.47), anastomotic leak (OR 3.94; 95% CI 1.88-8.24), wound infection (OR 2.22; 95% CI 1.47, 3.36), and pulmonary events (OR 2.10; 95% CI 1.18, 3.74) were all significantly increased. For pathological results, no statistical differences in the number of harvested lymph nodes and the positive margin were noted between the two groups.
conclusionsBased on a meta-analysis, obesity increases the conversion rate and postoperative morbidity of rectal cancer surgery but does not influence pathological results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.