Evidence map›Paper›PMID 26809819›Full record

ArticleBMC infectious diseases2016

Diarrhoeagenic Escherichia coli in mother-child Pairs in Ile-Ife, South Western Nigeria.

Babatunde W Odetoyin, Jennifer Hofmann, Aaron O Aboderin, Iruka N Okeke

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Shiga Toxin-ProducingMicroorganisms · 2025
    Review
  4. Article
  5. Antimicrobial Resistance in DiverseAntibiotics (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Suboptimal Bacteriological Quality of Household Water in Municipal Ibadan, Nigeria.The American journal of tropical medicine and hygiene · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Beneficial role of skim milk against drug-resistantNew microbes and new infections · 2022
    Article
  15. DiarrhoeagenicAfrican health sciences · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Pathotyping and Antibiotic Resistance Profiling ofBioMed research international · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Babatunde W OdetoyinDepartment of Medical Microbiology and Parasitology, Obafemi Awolowo University, Ile-Ife, Nigeria. odetoyin@yahoo.com.
Jennifer HofmannDepartment of Biology, Haverford College, 370 Lancaster Avenue, Haverford, PA, 19041, USA. jhofmann@haverford.edu.
Aaron O AboderinDepartment of Medical Microbiology and Parasitology, Obafemi Awolowo University, Ile-Ife, Nigeria. diipo_aboderin@yahoo.com.
Iruka N OkekeDepartment of Biology, Haverford College, 370 Lancaster Avenue, Haverford, PA, 19041, USA. iokeke@haverford.edu.
Obafemi Awolowo University · NGHaverford College · USUniversity of Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiarrhoeagenic Escherichia coli (DEC) pathotypes are among the most common bacterial causes of morbidity and mortality in young children. These pathogens are not sought routinely and capacity for their detection is limited in Africa. We investigated the distribution and dissemination of DEC in 126 children paired with their mothers in a Nigerian community.

methodsA total of 861 E. coli were isolated from 126 children with diarrhoea and their mothers. Antimicrobial susceptibility of each isolate was determined by Kirby-Bauer disc diffusion technique. All the isolates were screened for DEC markers by multiplex PCR. Genetic relatedness of DEC strains was determined by flagellin typing and Insertion element 3 (IS3)-based PCR.

resultsDEC were identified from 35.7% of individuals with the most common pathotype being shiga toxin-producing E. coli (42, 16.7%). Identical pathotypes were found in 13 (10.3%) of the mother-child pairs and in three of these strains from mothers and their children showed identical genetic signatures. Over 90% of DEC isolates were resistant to ampicillin, sulphonamide, tetracycline, streptomycin or trimethoprim, but only 9 (7.2%) were ciprofloxacin resistant

conclusionThe data suggest that healthy mothers are asymptomatic reservoirs of multiply-resistant strains that are pathogenic in their children and there are instances in which identical strains are found in mother-child pairs.

Indexed as

AdolescentAdultAmpicillinAnti-Bacterial AgentsChild, PreschoolCiprofloxacinDiarrheaDiarrhea, InfantileDisk Diffusion Antimicrobial TestsDNA Transposable ElementsEscherichia coliEscherichia coli InfectionsFemaleHumansInfantInfant, NewbornAmpicillinAnti-Bacterial AgentsCiprofloxacinDNA Transposable ElementsTetracycline

Identifiers

PMID26809819
PMCPMC4727348
OpenAlexW2264057289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.