Evidence map›Paper›PMID 26809804›Full record

ReviewPediatric nephrology (Berlin, Germany)2017

The path to chronic kidney disease following acute kidney injury: a neonatal perspective.

Swasti Chaturvedi, Kar Hui Ng, Cherry Mammen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 125 citations in OpenAlex.

  1. Pooled it
  2. Impact of maternal health on neonatal and long-term kidney outcomes.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Stealing nephrons-a review on how patent ductus arteriosus physiology impacts neonatal kidney health.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  11. Article
  12. Observational
  13. Neonatal acute kidney injury and neurodevelopmental impairment: investigating associations in very low birthweight infants.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  14. Article
  15. Evaluation of risk factors and outcomes of neonates with hypoxic ischemic encephalopathy and acute kidney injury.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Post-natal steroid exposure in very low birthweight neonates and associations with acute kidney injury.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Swasti ChaturvediKhoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Kar Hui NgKhoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Cherry MammenDivision of Paediatric Nephrology, Department of Paediatrics, British Columbia Children's Hospital, 4480 Oak Street, Vancouver, BC, Canada, V6H3V4. cmammen@cw.bc.ca.
National University Health System · SGBritish Columbia Children's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The risk of acute kidney injury (AKI) in hospitalized critically ill neonatal populations without primary renal disease continues to be high, in both term and premature infants. Observational studies have revealed high rates of chronic kidney disease (CKD) in survivors of neonatal AKI. Proposed mechanisms underlying the progression of CKD following AKI include nephron loss and hyperfiltration, vascular insufficiency and maladaptive repair mechanisms. Other factors, including prematurity and low birth weight, have an independent relationship with the development of CKD, but they may also be positive effect modifiers in the relationship of AKI and CKD. The large degree of heterogeneity in the literature on AKI in the neonatal population, including the use of various AKI definitions and CKD outcomes, has hampered the medical community's ability to properly assess the relationship of AKI and CKD in this vulnerable population. Larger prospective cohort studies with control groups which utilize recently proposed neonatal AKI definitions and standardized CKD definitions are much needed to properly quantify the risk of CKD following an episode of AKI. Until there is further evidence to guide us, we recommend that all neonates with an identified episode of AKI should have an appropriate longitudinal follow-up in order to identify CKD at its earliest stages.

Indexed as

Disease ProgressionAcute Kidney InjuryCase-Control StudiesCritical IllnessHumansInfantInfant, Extremely Low Birth WeightInfant, NewbornInfant, PrematureInfant, Premature, DiseasesIntensive Care Units, NeonatalKidney GlomerulusLongitudinal StudiesObservational Studies as TopicProportional Hazards ModelsRenal Insufficiency, ChronicAcute kidney injuryChronic kidney diseaseNeonateOutcomesPrematurity

Identifiers

PMID26809804
OpenAlexW2265329415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.