ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2016
Raw Garlic Consumption and Lung Cancer in a Chinese Population.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Cracking the Sulfur Code: Garlic Bioactive Molecules as Multi-Target Blueprints for Drug Discovery.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Combined effects of physical activity, cognitive activity, and dietary patterns on cognitive impairment in older adults with consideration of APOE genotype: a cohort study.Alzheimer's research & therapy · 2025Article
- Garlic consumption and risk of diabetes mellitus in the Chinese elderly: A population-based cohort study.Asia Pacific journal of clinical nutrition · 2025Article
- Release of elements and phenolic and flavonoid compounds from herbs and spices into acacia honey during infusion.Journal of food science and technology · 2025Article
- Association between the dietary inflammatory index and risk of lung cancer: a multi-centered case-control study.BMC cancer · 2024Article
- Exploring the health benefits of raw white garlic consumption in humans: a mini review.Frontiers in nutrition · 2024Review
- Article
- Garlic consumption and colorectal cancer risk in US adults: a large prospective cohort study.Frontiers in nutrition · 2023Article
- Method Validation, Residues and Dietary Risk Assessment for Procymidone in Green Onion and Garlic Plant.Foods (Basel, Switzerland) · 2022Article
- Association and mechanism of garlic consumption with gastrointestinal cancer risk: A systematic review and meta-analysis.Oncology letters · 2022Review
- Types of garlic and their anticancer and antioxidant activity: a review of the epidemiologic and experimental evidence.European journal of nutrition · 2021Review
- Identification of novel bioactive molecules from garlic bulbs: A special effort to determine the anticancer potential against lung cancer with targeted drugs.Saudi journal of biological sciences · 2020Article
- Raw garlic consumption is inversely associated with prehypertension in a large-scale adult population.Journal of human hypertension · 2020Article
- Bioactive Compounds and Biological Functions of Garlic (Foods (Basel, Switzerland) · 2019Review
- Consumption of garlic and its interactions with tobacco smoking and alcohol drinking on esophageal cancer in a Chinese population.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2019Article
- Garlic Consumption and All-Cause Mortality among Chinese Oldest-Old Individuals: A Population-Based Cohort Study.Nutrients · 2019Article
- Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress.Nutrients · 2018Article
- Diallyl Trisulfide Inhibits Growth of NCI-H460International journal of biological sciences · 2017Article
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11 authors.
Funding
Abstract
backgroundEvidence of anticancer properties of garlic for different cancer sites has been reported previously in in vitro and in vivo experimental studies but there is limited epidemiologic evidence on the association between garlic and lung cancer.
methodsWe examined the association between raw garlic consumption and lung cancer in a case-control study conducted between 2005 and 2007 in Taiyuan, China. Epidemiologic data was collected by face-to-face interviews from 399 incident lung cancer cases and 466 healthy controls. We used unconditional logistic regression models to estimate crude and adjusted ORs (aOR) and their 95% confidence intervals (CI). Adjusted models controlled for age, sex, average annual household income 10 years ago, smoking, and indoor air pollution.
resultsCompared with no intake, raw garlic intake was associated with lower risk of development of lung cancer with a dose-response pattern (aOR for <2 times/week = 0.56; 95% CI, 0.39-0.81 and aOR for ≥2 times/week = 0.50; 95% CI, 0.34-0.74; Ptrend = 0.0002). Exploratory analysis showed an additive interaction of raw garlic consumption with indoor air pollution and with any supplement use in association with lung cancer.
conclusionsThe results of the current study suggest that raw garlic consumption is associated with reduced risk of lung cancer in a Chinese population. IMPACT: This study contributes to the limited research in human population on the association between garlic and lung cancer and advocates further investigation into the use of garlic in chemoprevention of lung cancer. Cancer Epidemiol Biomarkers Prev; 25(4); 624-33. ©2016 AACR.
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