Evidence map›Paper›PMID 26808317›Full record

SynthesisPloS one2016

Panethnic Differences in Blood Pressure in Europe: A Systematic Review and Meta-Analysis.

Pietro Amedeo Modesti, Gianpaolo Reboldi, Francesco P Cappuccio, Charles Agyemang, Giuseppe Remuzzi, Stefano Rapi, Eleonora Perruolo, Gianfranco Parati, ESH Working Group on CV Risk in Low Resource Settings

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 660 papers, 130 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
660citing papers in PubMed, 130 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

660 citing papers in PubMed, 130 syntheses or guidelines pooled it.

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  4. Colorectal neoplasia-specific amino acid profiles and their diagnostic potential: a systematic review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  20. The Association Between Affect and Adiposity in Childhood and Adolescence: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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600 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pietro Amedeo ModestiDept of Medicina Sperimentale e Clinica, University of Florence, Florence, Italy.
Gianpaolo ReboldiDept of Medicine, University of Perugia, Perugia, Italy.
Francesco P CappuccioUniversity of Warwick, Warwick Medical School, and University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom.
Charles AgyemangDept of Public Health, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands.
Giuseppe RemuzziIRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, Dept. of Medicine, Unit of Nephrology, Dialysis and Transplantation, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
Stefano RapiDept of Medicina Sperimentale e Clinica, University of Florence, Florence, Italy.
Eleonora PerruoloDept of Medicina Sperimentale e Clinica, University of Florence, Florence, Italy.
Gianfranco ParatiDept of Health Sciences, University of Milano-Bicocca, Dept. of Cardiology, S. Luca Hospital, IRCCS Istituto Auxologico, Milano, Italy.
ESH Working Group on CV Risk in Low Resource Settings

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople of Sub Saharan Africa (SSA) and South Asians(SA) ethnic minorities living in Europe have higher risk of stroke than native Europeans(EU). Study objective is to provide an assessment of gender specific absolute differences in office systolic(SBP) and diastolic(DBP) blood pressure(BP) levels between SSA, SA, and EU. METHODS AND

findingsWe performed a systematic review and meta-analysis of observational studies conducted in Europe that examined BP in non-selected adult SSA, SA and EU subjects. Medline, PubMed, Embase, Web of Science, and Scopus were searched from their inception through January 31st 2015, for relevant articles. Outcome measures were mean SBP and DBP differences between minorities and EU, using a random effects model and tested for heterogeneity. Twenty-one studies involving 9,070 SSA, 18,421 SA, and 130,380 EU were included. Compared with EU, SSA had higher values of both SBP (3.38 mmHg, 95% CI 1.28 to 5.48 mmHg; and 6.00 mmHg, 95% CI 2.22 to 9.78 in men and women respectively) and DBP (3.29 mmHg, 95% CI 1.80 to 4.78; 5.35 mmHg, 95% CI 3.04 to 7.66). SA had lower SBP than EU(-4.57 mmHg, 95% CI -6.20 to -2.93; -2.97 mmHg, 95% CI -5.45 to -0.49) but similar DBP values. Meta-analysis by subgroup showed that SA originating from countries where Islam is the main religion had lower SBP and DBP values than EU. In multivariate meta-regression analyses, SBP difference between minorities and EU populations, was influenced by panethnicity and diabetes prevalence.

conclusions1) The higher BP in SSA is maintained over decades, suggesting limited efficacy of prevention strategies in such group in Europe;2) The lower BP in Muslim populations suggests that yet untapped lifestyle and behavioral habits may reveal advantages towards the development of hypertension;3) The additive effect of diabetes, emphasizes the need of new strategies for the control of hypertension in groups at high prevalence of diabetes.

Indexed as

Blood PressureEthnicityAdultEuropeFemaleHumansMale

Identifiers

PMID26808317
PMCPMC4725677

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.