SynthesisJournal of addiction medicine
A Systematic Review on the Use of Psychosocial Interventions in Conjunction With Medications for the Treatment of Opioid Addiction.
Synthesis in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 144 papers, 14 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multi-Tiered Safety Net Following Naloxone Resuscitation From Opioid Overdose
Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine
Enhancing Office-based Buprenorphine Treatment: An Adaptive Psychosocial Approach
Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics
Cognitive-Behavioral Therapy for Opioid Use Disorder: A Manualized Pilot Study
Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine
Who cites it
144 citing papers in PubMed, 14 syntheses or guidelines pooled it.
- Factors associated with the percentage of individuals who initiate and discontinue naltrexone as a relapse prevention pharmacotherapy in opioid use disorder: A systematic review, meta-analysis and meta-regression.Addiction (Abingdon, England) · 2026Pooled it
- Pooled it
- A systematic review and meta-analysis of psychosocial interventions for persons with comorbid anxiety and substance use disorders.Journal of substance use and addiction treatment · 2024Pooled it
- Applications of isradipine in human addiction studies: A systematic literature review.Experimental and clinical psychopharmacology · 2023Pooled it
- Management of opioid use disorder, opioid withdrawal, and opioid overdose prevention in hospitalized adults: A systematic review of existing guidelines.Journal of hospital medicine · 2022Pooled it
- Factors Associated with Long-Term Retention in Buprenorphine-Based Addiction Treatment Programs: a Systematic Review.Journal of general internal medicine · 2022Pooled it
- Effectiveness of medication for opioid use disorders in transition-age youth: A systematic review.Journal of substance abuse treatment · 2022Pooled it
- Adjunct interventions to standard medical management of buprenorphine in outpatient settings: A systematic review of the evidence.Drug and alcohol dependence · 2021Pooled it
- A systematic review of gene-by-intervention studies of alcohol and other substance use.Development and psychopathology · 2021Pooled it
- The role of social network support in treatment outcomes for medication for opioid use disorder: A systematic review.Journal of substance abuse treatment · 2021Pooled it
- Cognitive-behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis.Health technology assessment (Winchester, England) · 2021Pooled it
- The neurobiological reward system in Prolonged Grief Disorder (PGD): A systematic review.Psychiatry research. Neuroimaging · 2020Pooled it
- Pooled it
- Opioid use disorder in primary care: PEER umbrella systematic review of systematic reviews.Canadian family physician Medecin de famille canadien · 2019Pooled it
- Adjunctive Psychosocial Interventions and Opioid Abstinence Among Patients Receiving Buprenorphine: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Laboratory-induced stress and craving predict opioid use during follow-up among individuals with prescription opioid use disorder.Drug and alcohol dependence · 2021Trial
- Trial
- An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain.Drug and alcohol dependence · 2019Trial
- Medications for opioid use disorder, recovery supports, and overdose risk -- a database linkage study of a rural cohort of people who inject drugs and use opioids.BMC public health · 2026Article
- Treatment of opioid use disorder in pregnancy among individuals with and without co-occurring stimulant use disorder: A retrospective cohort study.Journal of substance use and addiction treatment · 2026Article
84 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Opioid use and overdose rates have risen to epidemic levels in the United States during the past decade. Fortunately, there are effective medications (ie, methadone, buprenorphine, and oral and injectable naltrexone) available for the treatment of opioid addiction. Each of these medications is approved for use in conjunction with psychosocial treatment; however, there is a dearth of empirical research on the optimal psychosocial interventions to use with these medications. In this systematic review, we outline and discuss the findings of 3 prominent prior reviews and 27 recent publications of empirical studies on this topic. The most widely studied psychosocial interventions examined in conjunction with medications for opioid addiction were contingency management and cognitive behavioral therapy, with the majority focusing on methadone treatment. The results generally support the efficacy of providing psychosocial interventions in combination with medications to treat opioid addictions, although the incremental utility varied across studies, outcomes, medications, and interventions. The review highlights significant gaps in the literature and provides areas for future research. Given the enormity of the current opioid problem in the United States, it is critical to gain a better understanding of the most effective ways to deliver psychosocial treatments in conjunction with these medications to improve the health and well-being of individuals suffering from opioid addiction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.