Evidence map›Paper›PMID 26807686›Full record

ArticleCritical care medicine2016

Psychiatric Symptoms in Acute Respiratory Distress Syndrome Survivors: A 1-Year National Multicenter Study.

Minxuan Huang, Ann M Parker, O Joseph Bienvenu, Victor D Dinglas, Elizabeth Colantuoni, Ramona O Hopkins, Dale M Needham, National Institutes of Health, National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network

Open access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 4 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 4 syntheses or guidelines pooled it, 151 citations in OpenAlex.

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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Minxuan Huang1Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins University School of Medicine, Baltimore, MD. 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. 3Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD. 4Department of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD. 5Pulmonary and Critical Care Division, Department of Medicine, Intermountain Medical Center, Murray, UT. 6Center for Humanizing Critical Care, Intermountain Healthcare, Murray, UT. 7Psychology Department and Neuroscience Center, Brigham Young University, Provo, UT. 8Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD.
Ann M Parker
O Joseph Bienvenu
Victor D Dinglas
Elizabeth Colantuoni
Ramona O Hopkins
Dale M Needham
National Institutes of Health, National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network
Lung Institute · USJohns Hopkins University · US

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Patient Outcomes 6 and 12 Months After ALTA, OMEGA and EDEN ARDS Network TrialsR01HL091760 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HOPKINS, RAMONA O, NEEDHAM, DALE MURRAY · 2008 to 2011
$2.0M
VITAMIN C, GLUTATHIONE, AND ENDOTHELIAL CELL FUNCTIONR01HL056170 · NHLBI · OREGON STATE UNIVERSITY · PI FREI, BALZ B · 1996 to 1999
–
NHLBI NIH HHS 3R01HL091760-02S1NHLBI NIH HHS 5T32HL00753432NHLBI NIH HHS N01 HR056170NHLBI NIH HHS R01 HL091760NHLBI NIH HHS R01HL091760NHLBI NIH HHS T32 HL007534PHS HHS HHSN268200536165CPHS HHS HHSN268200536175CPHS HHS HHSN268200536179C
6 · The paper itself

Abstract

objectiveTo evaluate prevalence, severity, and co-occurrence of and risk factors for depression, anxiety, and posttraumatic stress disorder symptoms over the first year after acute respiratory distress syndrome.

designProspective longitudinal cohort study. SETTINGS: Forty-one Acute Respiratory Distress Syndrome Network hospitals across the United States. PATIENTS: Six hundred ninety-eight acute respiratory distress syndrome survivors.

interventionsNone. MEASUREMENTS AND MAIN

resultsPsychiatric symptoms were evaluated by using the Hospital Anxiety and Depression Scale and Impact of Event Scale-Revised at 6 and 12 months. Adjusted prevalence ratios for substantial symptoms (binary outcome) and severity scores were calculated by using Poisson and linear regression, respectively. During 12 months, a total of 416 of 629 patients (66%) with at least one psychiatric outcome measure had substantial symptoms in at least one domain. There was a high and almost identical prevalence of substantial symptoms (36%, 42%, and 24% for depression, anxiety, and posttraumatic stress disorder) at 6 and 12 months. The most common pattern of co-occurrence was having symptoms of all three psychiatric domains simultaneously. Younger age, female sex, unemployment, alcohol misuse, and greater opioid use in the ICU were significantly associated with psychiatric symptoms, whereas greater severity of illness and ICU length of stay were not associated.

conclusionsPsychiatric symptoms occurred in two thirds of acute respiratory distress syndrome survivors with frequent co-occurrence. Sociodemographic characteristics and in-ICU opioid administration, rather than traditional measures of critical illness severity, should be considered in identifying the patients at highest risk for psychiatric symptoms during recovery. Given high co-occurrence, acute respiratory distress syndrome survivors should be simultaneously evaluated for a full spectrum of psychiatric sequelae to maximize recovery.

Indexed as

AdultAgedAge FactorsAnalgesics, OpioidAnxietyDepressionFemaleHumansIntensive Care UnitsMaleMiddle AgedProspective StudiesPsychiatric Status Rating ScalesQuality of LifeRespiratory Distress SyndromeRisk FactorsAnalgesics, Opioid

Identifiers

PMID26807686
PMCPMC4833555
OpenAlexW2314180516

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.