Evidence map›Paper›PMID 26807427›Full record

ArticleOpen forum infectious diseases2016

A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa.

Anna Gamell, Lukas Muri, Alex Ntamatungiro, Daniel Nyogea, Lameck B Luwanda, Christoph Hatz, Manuel Battegay, Ingrid Felger, Marcel Tanner, Thomas Klimkait and 1 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anna GamellSwiss Tropical and Public Health Institute, Basel; University of Basel; Ifakara Health Institute, United Republic of Tanzania.
Lukas MuriSwiss Tropical and Public Health Institute, Basel; University of Basel.
Alex NtamatungiroIfakara Health Institute , United Republic of Tanzania.
Daniel NyogeaIfakara Health Institute , United Republic of Tanzania.
Lameck B LuwandaIfakara Health Institute , United Republic of Tanzania.
Christoph HatzSwiss Tropical and Public Health Institute, Basel; University of Basel.
Manuel BattegayUniversity of Basel; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel.
Ingrid FelgerSwiss Tropical and Public Health Institute, Basel; University of Basel.
Marcel TannerSwiss Tropical and Public Health Institute, Basel; University of Basel.
Thomas KlimkaitMolecular Virology, Department Biomedicine-Petersplatz , University of Basel , Switzerland.
Emilio LetangSwiss Tropical and Public Health Institute, Basel; University of Basel; Ifakara Health Institute, United Republic of Tanzania; ISGLOBAL, Barcelona Centre for International Health Research, Hospital Clínic-Universitat de Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acquisition of drug-resistance mutations among African children living with in human immunodeficiency virus on antiretroviral treatment has been scarcely reported. This threatens the overall success of antiretroviral programs and the clinical outcomes of children in care. We present a well characterized series of children from rural Tanzania with acquired drug-resistance mutations to contribute to the better understanding of this emerging public health concern.

Indexed as

Africaantiretroviral treatmentchildrenHIVresistance mutations

Identifiers

PMID26807427
PMCPMC4722282

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.