SynthesisBrain and behavior2015
Correlations between arm motor behavior and brain function following bilateral arm training after stroke: a systematic review.
Synthesis in Brain and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Examining the effectiveness of virtual, augmented, and mixed reality (VAMR) therapy for upper limb recovery and activities of daily living in stroke patients: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitation · 2022Pooled it
- The modulatory effects of bilateral arm training (BAT) on the brain in stroke patients: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- Effectiveness of Virtual Reality in the Rehabilitation of Motor Function of Patients With Subacute Stroke: A Meta-Analysis.Frontiers in neurology · 2021Pooled it
- Correlations between arm motor behavior and brain function following bilateral arm training after stroke: a systematic review.Brain and behavior · 2015Pooled it
- Behavioral and neurophysiological changes associated with a single session of bimanual task practice after stroke.Clinical neurophysiology practice · 2026Article
- The efficacy of virtual reality-based rehabilitation in improving motor function in patients with stroke: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Review
- Experimental Evaluation of EMKEY: An Assistive Technology for People with Upper Limb Disabilities.Sensors (Basel, Switzerland) · 2023Article
- The Route of Motor Recovery in Stroke Patients Driven by Exoskeleton-Robot-Assisted Therapy: A Path-Analysis.Medical sciences (Basel, Switzerland) · 2021Article
- Impairment and Compensation in Dexterous Upper-Limb Function After Stroke. From the Direct Consequences of Pyramidal Tract Lesions to Behavioral Involvement of Both Upper-Limbs in Daily Activities.Frontiers in human neuroscience · 2021Review
- Data on a new neurorehabilitation approach targeting functional recovery in stroke patients.Data in brief · 2019Article
- Skillful Cycling Training Induces Cortical Plasticity in the Lower Extremity Motor Cortex Area in Healthy Persons.Frontiers in neuroscience · 2019Article
- A Review on the Relationship Between Sound and Movement in Sports and Rehabilitation.Frontiers in psychology · 2019Review
- Arm Ability Training (AAT) Promotes Dexterity Recovery After a Stroke-a Review of Its Design, Clinical Effectiveness, and the Neurobiology of the Actions.Frontiers in neurology · 2018Review
- Exoskeleton-Robot Assisted Therapy in Stroke Patients: A Lesion Mapping Study.Frontiers in neuroinformatics · 2018Article
- Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study.Neural plasticity · 2018Article
- Consecutive learning of opposing unimanual motor tasks using the right arm followed by the left arm causes intermanual interference.PloS one · 2017Article
- Improving a Bimanual Motor Skill Through Unimanual Training.Frontiers in integrative neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundBilateral training (BT) of the upper limb (UL) might enhance recovery of arm function after stroke. To better understand the therapeutic potential of BT, this study aimed to determine the correlation between arm motor behavior and brain structure/function as a result of bilateral arm training poststroke.
methodsA systematic review of quantitative studies of BT evaluating both UL motor behavior and neuroplasticity was conducted. Eleven electronic databases were searched. Two reviewers independently selected studies, extracted data and assessed methodological quality, using the Effective Public Health Practice Project (EPHPP) tool.
resultsEight studies comprising 164 participants met the inclusion criteria. Only two studies rated "strong" on the EPHPP tool. Considerable heterogeneity of participants, BT modes, comparator interventions and measures contraindicated pooled outcome analysis. Modes of BT included: in-phase and anti-phase; functional movements involving objects; and movements only. Movements were mechanically coupled, free, auditory-cued, or self-paced. The Fugl-Meyer Assessment (UL section) was used in six of eight studies, however, different subsections were used by different studies. Neural correlates were measured using fMRI and TMS in three and five studies, respectively, using a wide variety of variables. Associations between changes in UL function and neural plasticity were inconsistent and only two studies reported a statistical correlation following BT.
conclusionsNo clear pattern of association between UL motor and neural response to BT was apparent from this review, indicating that the neural correlates of motor behavior response to BT after stroke remain unknown. To understand the full therapeutic potential of BT and its different modes, further investigation is required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.