ArticleMolecular and clinical oncology2015
Reasons for cancer metastasis: A holistic perspective.
Article in Molecular and clinical oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Clear cell sarcoma of the kidney with inferior vena cava tumor thrombus in a pediatric patient: a case report.The Canadian journal of urology · 2026Review
- Intratumoural metastasis of primary lung adenocarcinoma to non-invasive follicular thyroid neoplasm with papillary-like nuclear features.Pathologica · 2023Article
- Artemisinin inhibits the development of esophageal cancer by targeting HIF-1α to reduce glycolysis levels.Journal of gastrointestinal oncology · 2022Article
- Starvation mediates pancreatic cancer cell sensitivity to ferroptosis via ERK1/2, JNK and changes in the cell mesenchymal state.International journal of molecular medicine · 2022Article
- Clinicopathologic and genomic characterizations of brain metastases using a comprehensive genomic panel.Frontiers in medicine · 2022Article
- Evaluation of Monocarboxylate Transporter 4 (Frontiers in cell and developmental biology · 2021Article
- MCT4 has a potential to be used as a prognostic biomarker - a systematic review and meta-analysis.Oncology reviews · 2019Article
- Evaluation of metastatic niches in distant organs after surgical removal of tumor-bearing lymph nodes.BMC cancer · 2018Article
- Epithelial-mesenchymal transition as strategic microenvironment mimicry for cancer cell survival and immune escape?Genes & diseases · 2017Article
- Treatment of advanced solid tumours with NSAIDs: Correlation of quantitative monitoring of circulating tumour cells and positron emission tomography-computed tomography imaging.Oncology letters · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
Over several years, scientists investigating cancer have focused their efforts on elucidating the mechanisms underlying cancer metastasis, with the aim of finding a way to inhibit this process. These mechanisms, however, only explain the process of cancer metastasis, but do not explain why cancer would metastasize in the first place. Cancer metastasizes due to several factors, namely attack by the immune system, lack of oxygen and necessary nutrients, large amounts of lactic acid produced by glycolysis and increased cell death. Therefore, the majority of the presently available treatments for cancer also bear the potential to induce metastasis. Thus, it is crucial in medical practice to minimize the risk of cancer metastasis during a time when there are no effective means to inhibit this process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.