Evidence map›Paper›PMID 26807206›Full record

ReviewWorld journal of hepatology2016

Hepatitis C virus and non-Hodgkin's lymphomas: Meta-analysis of epidemiology data and therapy options.

Gabriele Pozzato, Cesare Mazzaro, Luigino Dal Maso, Endri Mauro, Francesca Zorat, Giulia Moratelli, Pietro Bulian, Diego Serraino, Valter Gattei

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. HCV infection and non-Hodgkin lymphomas: an evolving story.Clinical and experimental medicine · 2020
    Review
  7. Article
  8. Review
  9. Review
  10. Hepatitis C virus and the kidney.Nature reviews. Nephrology · 2019
    Review
  11. Article
  12. Extrahepatic cancers and chronic HCV infection.Nature reviews. Gastroenterology & hepatology · 2018
    Review
  13. Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Gabriele PozzatoGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Cesare MazzaroGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Luigino Dal MasoGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Endri MauroGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Francesca ZoratGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Giulia MoratelliGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Pietro BulianGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Diego SerrainoGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Valter GatteiGabriele Pozzato, Francesca Zorat, Giulia Moratelli, Department of Medical and Surgical Sciences, University of Trieste, 34100 Trieste, Italy.
Centro di Riferimento Oncologico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) is a global health problem affecting a large fraction of the world's population: This virus is able to determine both hepatic and extrahepatic diseases. Mixed cryoglobulinemia, a B-cell "benign" lymphoproliferative disorders, represents the most closely related as well as the most investigated HCV-related extrahepatic disorder. Since this virus is able to determine extrahepatic [non-Hodgkin's lymphoma (NHL)] as well as hepatic malignancies (hepatocellular carcinoma), HCV has been included among human cancer viruses. The most common histological types of HCV-associated NHL are the marginal zone, the lymphoplasmacytic and diffuse large cell lymphomas. The role of the HCV in the pathogenesis of the B-cell lymphoproliferative disorders is confirmed also by the responsiveness of the NHL to antiviral therapy. The purpose of this review is to provide an overview of the recent literature and a meta analysis of the epidemiology data, to explain the role of HCV in the development of NHL's lymphoma. Furthermore, the possibility to treat these HCV-related NHL with the antiviral therapy or with other therapeutic options, like chemotherapy, is also discussed.

Indexed as

Alpha-interferonHepatitis C virusHepatitis C virus genotypesNon-Hodgkin’s lymphoma

Identifiers

PMID26807206
PMCPMC4716526
OpenAlexW2288792905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.