ReviewWorld journal of hepatology2016
Hepatitis C virus infection and thyroid autoimmune disorders: A model of interactions between the host and the environment.
Review in World journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Impact of oncogenic viruses on autoimmune diseases and tumorigenesis.Infectious agents and cancer · 2026Review
- Article
- Do oxidized low-density lipoproteins link to extra hepatic manifestations in chronic, non-cirrhotic HCV patients?Metabolism open · 2025Article
- Viral infection and thyroid disorders: a narrative review.Frontiers in microbiology · 2025Review
- Article
- Silent Thyroiditis Associated with Ropeginterferon α-2b in a Patient with Polycythemia Vera.Internal medicine (Tokyo, Japan) · 2024Article
- Thyroid Autoimmunity and SARS-CoV-2 Infection.Journal of clinical medicine · 2023Review
- Medical Applications of Molecular Biotechnologies in the Context of Hashimoto's Thyroiditis.Diagnostics (Basel, Switzerland) · 2023Review
- A Literature Review on SARS-CoV-2 and Other Viruses in Thyroid Disorders: Environmental Triggers or No-Guilty Bystanders?International journal of environmental research and public health · 2023Review
- T memory stem cell characteristics in autoimmune diseases and their promising therapeutic values.Frontiers in immunology · 2023Review
- Burden, Outcome, and Comorbidities of Extrahepatic Manifestations in Hepatitis C Virus Infection.Biology · 2022Review
- Association between Anti-Hepatitis C Viral Intervention Therapy and Risk of Sjögren's Syndrome: A National Retrospective Analysis.Journal of clinical medicine · 2022Article
- Association of interferon-based therapy with risk of autoimmune diseases in patients with chronic hepatitis C virus infection: A population-based Taiwanese cohort study.Frontiers in immunology · 2022Article
- A Prospective Observational Study of 42 Patients with COVID-19 infection and a History of Hepatitis C Virus Infection and Thyroid Disease with Follow-Up Thyroid Function and Autoantibody Testing.Medical science monitor : international medical journal of experimental and clinical research · 2021Observational
- The interplay between thyroid and liver: implications for clinical practice.Journal of endocrinological investigation · 2020Review
- A Case of Graves' Disease Accompanied with Acute Hepatitis A Virus Infection.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2018Article
- Environmental Issues in Thyroid Diseases.Frontiers in endocrinology · 2017Review
- The role of human parvovirus B19 and hepatitis C virus in the development of thyroid disorders.Reviews in endocrine & metabolic disorders · 2016Review
- Chronic hepatitis C virus infection in India: Regional demographics and distribution of viral genotypes.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2016Article
- The impact of COVID 19 infection on HCV-induced thyroid disease.Acta endocrinologica (Bucharest, Romania : 2005)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hepatitis C virus (HCV) infection is an important public health problem and it is associated with hepatic and extrahepatic manifestations. Autoimmune thyroid diseases are common in HCV infected patients and the standard interferon-based treatment is associated with an increase of the immune-mediated thyroid damage. Recent evidence in the literature analyzed critical points of the mechanisms of thyroid damage, focusing on the balance between the two sides of the interaction: The environment (virus infection with potential cross-reaction) and the host (susceptibility genes with consistent immune response). The spectrum of antiviral treatment for chronic HCV infection is rapidly expanding for the development of dual o triple therapy. The availability of interferon-free combined treatment with direct antiviral agents for HCV is very promising, in order to ameliorate the patient compliance and to reduce the development of thyroid autoimmunity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.