Evidence map›Paper›PMID 26807176›Full record

ArticleAmerican journal of translational research2015

Healing of cancellous fracture in a novel mouse model.

Duanyang Han, Na Han, Yixun Chen, Peixun Zhang, Baoguo Jiang

Abstract read
In one paragraph

Article in American journal of translational research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Duanyang HanDepartment of Orthopedics and Trauma, Peking University People's Hospital China.
Na HanDepartment of Orthopedics and Trauma, Peking University People's Hospital China.
Yixun ChenDepartment of Orthopedics and Trauma, Peking University People's Hospital China.
Peixun ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital China.
Baoguo JiangDepartment of Orthopedics and Trauma, Peking University People's Hospital China.

Funding

EtOH Modulation of Synaptic Plasticity in Nucleus AccumbensR01AA020501 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MARTIN, GILLES E · 2012 to 2016
$1.6M
NIAAA NIH HHS R01 AA020501
6 · The paper itself

Abstract

Fractures are one of the most prevalent clinical conditions worldwide. Among them, cancellous fracture is a major cause of extremities fractures. Unfortunately, it is largely unknown about how is the healing of cancellous fracture. In the current study, we present a novel cancellous fracture mice model, which successfully mimic clinical cancellous fracture scenario. Next, we showed that the newly repaired trabeculae in fracture healing zone were thicker than normal bone tissue with more sufficient local blood supply. There are more osteoclasts reside in the fracture healing zone than normal bone tissue and these osteoclasts distributed more closely and densely. Moreover, the early repairing bone mass in fracture healing zone was not fully collagen loaded as normal bone tissue. Comparing to similar cell proliferation activity, upregulated local cell function play more important role in the cancellous fracture repair.

Indexed as

Cancellous fracturefracture healingmouse model

Identifiers

PMID26807176
PMCPMC4697708

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.