Evidence map›Paper›PMID 26806984›Full record

ArticleSynthesis2015

Iron-Catalyzed Diastereoselective Intramolecular Olefin Aminobromination with Bromide Ion.

Jun-Shan Tian, Cheng-Liang Zhu, Yun-Rong Chen, Hao Xu

Abstract read
In one paragraph

Article in Synthesis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Process Safety Assessment of the Iron-Catalyzed 1,2-Organic process research & development · 2026
    Article
  2. Article
  3. Iron-catalyzed domino coupling reactions of π-systems.Beilstein journal of organic chemistry · 2021
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jun-Shan TianDepartment of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
Cheng-Liang ZhuDepartment of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
Yun-Rong ChenDepartment of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
Hao XuDepartment of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.

Funding

Selective Nitrogen Atom Transfer for Applications in Biomedical SciencesR01GM110382 · NIGMS · GEORGIA STATE UNIVERSITY · PI XU, HAO · 2014 to 2019
$1.9M
NIGMS NIH HHS R01 GM110382
6 · The paper itself

Abstract

A new iron-catalyzed diastereoselective aminobromination method is reported for both internal and terminal olefins (yield up to 90% and dr up to >20:1). In this transformation, a functionalized hydroxylamine and bromide ion were used as the nitrogen and bromine source, respectively. This method is compatible with a broad range of olefins and provides a convenient approach to synthetically valuable vicinal bromo primary amines. Our studies suggest that both the diastereoselectivity and enantioselectivity for the olefin aminobromination can be controlled by iron catalysts.

Indexed as

alkenesbrominediastereoselectivityironnitrogen

Identifiers

PMID26806984
PMCPMC4720155

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.