Evidence map›Paper›PMID 26806652›Full record

ArticleAdvanced healthcare materials2016

Click-Crosslinked Injectable Gelatin Hydrogels.

Sandeep T Koshy, Rajiv M Desai, Pascal Joly, Jianyu Li, Rishi K Bagrodia, Sarah A Lewin, Neel S Joshi, David J Mooney

Open access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 169 citations in OpenAlex.

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  14. Photochemical Control of Network Topology in PEG Hydrogels.Advanced materials (Deerfield Beach, Fla.) · 2024
    Article
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Sandeep T KoshyWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
Rajiv M DesaiWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
Pascal JolyWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
Jianyu LiWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
Rishi K BagrodiaWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
Sarah A LewinWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
Neel S JoshiWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
David J MooneyWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
Harvard University · US

Funding

ENGINEERING SKELETAL MUSCLE WITH BIODEGRADABLE HYDROGELSR01DE013349 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOONEY, DAVID J · 2000 to 2022
$9.3M
Biomaterial based breast cancer vaccineR01EB015498 · NIBIB · HARVARD MEDICAL SCHOOL · PI MOONEY, DAVID J · 2013 to 2016
$1.5M
Howard Hughes Medical InstituteNIBIB NIH HHS R01 EB015498NIDCR NIH HHS R01 DE013349
6 · The paper itself

Abstract

Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for high viability of encapsulated cells, establishment of 3D elongated cell morphologies, and biodegradation when injected in vivo.

Indexed as

3T3 CellsAnimalsCell AdhesionCell ProliferationCell ShapeClick ChemistryCross-Linking ReagentsFemaleGelatinHydrogelsMiceSubcutaneous TissueCross-Linking ReagentsGelatinHydrogelsclick chemistrydegradablegelatinhydrogelsinjectable

Identifiers

PMID26806652
PMCPMC4849477
OpenAlexW2259823352

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.