Evidence map›Paper›PMID 26806384›Full record

ReviewMicrobes and infection2016

Candida albicans biofilms: development, regulation, and molecular mechanisms.

Megha Gulati, Clarissa J Nobile

Abstract readReview
In one paragraph

Review in Microbes and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 341 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
341citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

341 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Preventive action of ketamine alone and in combination with antifungals on Candida biofilm formation in catheters.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  4. Beyond roughness: Lateral surface architecture drives Candida albicans virulence on denture polymers.Dental materials : official publication of the Academy of Dental Materials · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Phenotypic and genotypic analysis ofInfection and immunity · 2026
    Article
  14. International journal of molecular sciences · 2026
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

281 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Megha GulatiDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, Merced, CA, USA.
Clarissa J NobileDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, Merced, CA, USA. Electronic address: cnobile@ucmerced.edu.

Funding

Genetic Analysis of the Transcriptional Network Governing C. albicans BiofilmsR00AI100896 · NIAID · UNIVERSITY OF CALIFORNIA, MERCED · PI NOBILE, CLARISSA JANE · 2014 to 2015
$498k
NIAID NIH HHS R00 AI100896
6 · The paper itself

Abstract

A major virulence attribute of Candida albicans is its ability to form biofilms, densely packed communities of cells adhered to a surface. These biofilms are intrinsically resistant to conventional antifungal therapeutics, the host immune system, and other environmental factors, making biofilm-associated infections a significant clinical challenge. Here, we review current knowledge on the development, regulation, and molecular mechanisms of C. albicans biofilms.

Indexed as

Gene Expression Regulation, FungalBiofilmsCandida albicansHumansVirulenceBiofilmCandida albicansFungiMicrobial communityPathogenTranscriptional regulation

Identifiers

PMID26806384
PMCPMC4860025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.