Evidence map›Paper›PMID 26806071›Full record

ArticleThe Analyst2016

Genetically anchored fluorescent probes for subcellular specific imaging of hydrogen sulfide.

Jianwei Chen, Mingkun Zhao, Xiqian Jiang, Antons Sizovs, Meng C Wang, Christopher R Provost, Jia Huang, Jin Wang

Abstract read
In one paragraph

Article in The Analyst, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jianwei Chen *Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030, U.S.A.
Mingkun Zhao *Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX 77030, U.S.A.
Xiqian JiangDepartment of Pharmacology, Baylor College of Medicine, Houston, TX 77030, U.S.A.
Antons SizovsDepartment of Pharmacology, Baylor College of Medicine, Houston, TX 77030, U.S.A.
Meng C WangDepartment of Molecular and Human Genetics and Huffington Centre on Aging, Baylor College of Medicine, Houston, TX 77030, U.S.A.
Christopher R ProvostNew England Biolabs, Ipswich, MA 01938, U.S.A.
Jia HuangSciclotron LLC., Sugar Land, TX 77479, U.S.A.
Jin WangDepartment of Pharmacology, Baylor College of Medicine, Houston, TX 77030, U.S.A.

Funding

Prebiotic Regulation of LongevityR01AT009050 · NCCIH · BAYLOR COLLEGE OF MEDICINE · PI WANG, MENG CARLA · 2016 to 2020
$2.6M
LIPID SIGNALING IN REGULATION OF LONGEVITYR01AG045183 · NIA · BAYLOR COLLEGE OF MEDICINE · PI WANG, MENG CARLA · 2013 to 2017
$1.8M
REAL-TIME QUANTITATIVE IMAGING OF INTRACELLULAR BIOTHIOL DYNAMICSR01GM115622 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI WANG, JIN · 2015 to 2019
$1.6M
NCCIH NIH HHS R01 AT009050NIA NIH HHS R01 AG045183NIA NIH HHS R01-AG045183NIGMS NIH HHS R01 GM115622NIGMS NIH HHS R01-GM115622PHS HHS 56338
6 · The paper itself

Abstract

Imaging hydrogen sulfide (H2S) at the subcellular resolution will greatly improve the understanding of functions of this signaling molecule. Taking advantage of the protein labeling technologies, we report a general strategy for the development of organelle specific H2S probes, which enables sub-cellular H2S imaging essentially in any organelles of interest.

Indexed as

Genetic TechniquesHeLa CellsHumansHydrogen SulfideIntracellular SpaceLuminescent ProteinsMolecular ImagingHydrogen SulfideLuminescent Proteins

Identifiers

PMID26806071
PMCPMC4747831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.