Evidence map›Paper›PMID 26805890›Full record

ArticleJournal of personalized medicine2016

Information Technology Support for Clinical Genetic Testing within an Academic Medical Center.

Samuel Aronson, Lisa Mahanta, Lei Lei Ros, Eugene Clark, Lawrence Babb, Michael Oates, Heidi Rehm, Matthew Lebo

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. An eMERGE Clinical Center at Partners Personalized Medicine.Journal of personalized medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Samuel AronsonPartners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. saronson@partners.org.
Lisa MahantaPartners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. lmahanta@partners.org.
Lei Lei RosPartners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. lhros@partners.org.
Eugene ClarkPartners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. ehclark@partners.org.
Lawrence BabbPartners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. lbabb@geneinsight.com.
Michael OatesPartners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. mfoates@partners.org.
Heidi RehmPartners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. hrehm@partners.org.
Matthew LeboPartners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. mlebo@partners.org.
Mass General Brigham · USBrigham and Women's Hospital · USBroad Institute · US

Funding

Finding Genomic Profiles of COVID-19 Phenotypes from the EHRU01HG008685 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIZABETH W KARLSON, Matthew S Lebo · 2015 to 2026
$13.6M
Integration of Whole Genome Sequencing into Clinical MedicineU01HG006500 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI GREEN, ROBERT C. · 2012 to 2016
$11.5M
Genome Sequence-Based Screening for Childhood Risk and Newborn IllnessU19HD077671 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI BEGGS, ALAN H., GREEN, ROBERT C. · 2013 to 2018
$6.1M
NHGRI NIH HHS U01 HG006500NHGRI NIH HHS U01 HG008685NICHD NIH HHS U19 HD077671
6 · The paper itself

Abstract

Academic medical centers require many interconnected systems to fully support genetic testing processes. We provide an overview of the end-to-end support that has been established surrounding a genetic testing laboratory within our environment, including both laboratory and clinician facing infrastructure. We explain key functions that we have found useful in the supporting systems. We also consider ways that this infrastructure could be enhanced to enable deeper assessment of genetic test results in both the laboratory and clinic.

Indexed as

GeneInsightgenetic testing processGIGPADinformation technology supportLIMSLIS

Identifiers

PMID26805890
PMCPMC4810383
OpenAlexW2271907546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.