ArticleSingapore medical journal2017
An evaluation of factors affecting adherence to antiepileptic drugs in patients with epilepsy: a cross-sectional study.
Article in Singapore medical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Factors Associated With Antiseizure Medication Adherence in Patients With Epilepsy: A Systematic Review.Brain and behavior · 2026Pooled it
- Prevalence, characteristics, and treatment outcomes of epilepsy in Nigeria: a systematic review and meta-analysis.European journal of medical research · 2025Pooled it
- Treatment patterns and adverse events of antiseizure medications among adult patients with epilepsy: a single centre observational cross-sectional study in Northern Sri Lanka.BMC neurology · 2026Observational
- Medication adherence in epilepsy: the role of adverse drug reactions and patient knowledge-attitude-behavior.Acta epileptologica · 2026Article
- Multicentric study of adherence to antiseizure medications among adults with epilepsy attended in neurology departments in Burkina Faso.Epilepsia open · 2025Article
- Anti-seizure Medication Adherence among Adolescents with Epilepsy in a Tertiary Hospital in the Philippines.Acta medica Philippina · 2025Article
- Danish population based study of familial epilepsy and childhood cancer.European journal of epidemiology · 2024Article
- A study to assess medication adherence and quality of life among epilepsy patients seeking treatment at AIIMS Bhopal.Journal of family medicine and primary care · 2024Article
- Pharmacist's Impact on Medication Adherence and Drug-Related Problems in Patients with Epilepsy.Turkish journal of pharmaceutical sciences · 2024Article
- Adherence to anti-seizure medications and self-reported availability and affordability of the medications in Addis Ababa, Ethiopia.PloS one · 2024Article
- Pattern of anti-epileptic medications nonadherence and associated factors at ambulatory clinic of Jimma Medical Center, Southwestern Ethiopia: A prospective observational study.SAGE open medicine · 2023Article
- Prevalence and associated factors of medication-related problems among epileptic patients at ambulatory clinic of Mettu Karl Comprehensive Specialized Hospital: a cross-sectional study.Journal of pharmaceutical policy and practice · 2022Article
- Non-Adherence to Antiepileptic Drugs and Associated Factors among Epileptic Patients at Ambulatory Clinic of Southwestern Ethiopian Hospital: A Cross-Sectional Study.Patient preference and adherence · 2022Article
- Drug therapy problems and predicting factors among ambulatory epileptic patients in Jimma Medical Center, Southwest Ethiopia.PloS one · 2022Observational
- Non-Adherence to Anti-Epileptic Drugs and Associated Factors among Epileptic Patients in Dessie Town Public Hospitals, Northeast Ethiopia.Journal of epilepsy research · 2021Article
- Factors Associated with Poor Antiepileptic Drugs Adherence in Below Poverty Line Persons with Epilepsy: A Cross-Sectional Study.Journal of neurosciences in rural practice · 2021Article
- Simultaneous Use of Two Different Tools to Assess Compliance with Antiepileptic Drugs: Experience in A Community-Based Study.Journal of neurosciences in rural practice · 2020Article
- Effectiveness, retention, and safety of modified ketogenic diet in adults with epilepsy at a tertiary-care centre in the UK.Journal of neurology · 2020Article
- Nonadherence to Antiepileptic Medications and Its Determinants among Epileptic Patients at the University of Gondar Referral Hospital, Gondar, Ethiopia, 2019: An Institutional-Based Cross-Sectional Study.Neurology research international · 2020Article
- Epilepsy Treatment Outcome and Its Predictors among Ambulatory Patients with Epilepsy at Mizan-Tepi University Teaching Hospital, Southwest Ethiopia.Neurology research international · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAdherence to antiepileptic drug (AED) therapy is important for controlling seizures in patients with epilepsy (PWE). It is vital to identify the factors influencing adherence to AED therapy using validated tools. This study aimed to evaluate the pattern and extent of AED adherence among PWE and to identify the factors that influence adherence.
methodsThis was a cross-sectional study involving PWE who had a confirmed diagnosis. Treatment adherence was assessed using the four-item Morisky Medication Adherence Scale. Univariate analysis with chi-square test was used to observe the association between different variables and AED adherence. Binary logistic regression analysis was used to identify the predictors of adherence.
results451 PWE (mean age 27.3 ± 8.1 years) were enrolled in the study; 251 (55.7%) were male and 198 (43.9%) were from the lower socioeconomic class. 326 (72.3%) patients had high adherence to AED therapy, while 125 (27.7%) had low adherence. AED adherence was significantly associated with socioeconomic status (p = 0.043) and type of epilepsy (p = 0.033). However, no significant difference was observed between adherence and age, gender, marital status, epilepsy duration, number and type of AEDs, and occurrence of adverse drug reactions. Patients with focal epilepsy and those from the middle/lower-middle socioeconomic classes were less likely to be nonadherent. The primary reason for nonadherence was forgetfulness.
conclusionThis study found that a majority of PWE have optimal rates of AED adherence and that forgetfulness is the primary reason for nonadherence among PWE.
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