Evidence map›Paper›PMID 26804937›Full record

ArticleInjury2016

Identifying gaps for research prioritisation: Global burden of external causes of injury as reflected in the Cochrane Database of Systematic Reviews.

Chante Karimkhani, Ritika Trikha, Baran Aksut, Trevor Jones, Lindsay N Boyers, Megan Schlichte, Hannah Pederson, Tyler Okland, Carolyn DiGuiseppi, Mona Nasser and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Injury, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Research prioritization of men's health and urologic diseases.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 3 countries.

Chante KarimkhaniColumbia University College of Physicians and Surgeons, New York, NY, USA.
Ritika TrikhaRosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Baran AksutColumbia University Medical Center, New York, NY, USA.
Trevor JonesUniversity of Arizona College of Medicine, Tucson, AZ, USA.
Lindsay N BoyersGeorgetown University School of Medicine, Washington DC, USA.
Megan SchlichteBaylor College of Medicine, Houston, TX, USA.
Hannah PedersonUniversity of Colorado School of Medicine, Aurora, CO, USA.
Tyler OklandUniversity of Colorado School of Medicine, Aurora, CO, USA.
Carolyn DiGuiseppiDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, CO, USA.
Mona NasserPeninsula Dental School, Plymouth University, Plymouth, UK.
Mohsen NaghaviInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Theo VosInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Sze Lin YoongHunter New England Population Health, NSW, Australia; The University of Newcastle, NSW, Australia.
Luke WolfendenHunter New England Population Health, NSW, Australia; The University of Newcastle, NSW, Australia.
Christopher J L MurrayInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Robert P DellavalleDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, CO, USA; Department of Dermatology, University of Colorado Anschutz Medical Campus, CO, USA; Department of Dermatology, Denver Veterans Administration Hospital, CO, USA. Electronic address: robert.dellavalle@ucdenver.edu.
Institute for Health Metrics and Evaluation · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · USUniversity of Newcastle Australia · AUBaylor College of Medicine · USColumbia University · USColumbia University Irving Medical Center · USGeorgetown University · USRosalind Franklin University of Medicine and Science · USUniversity of Arizona · USUniversity of Plymouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceBurden of disease should impact research prioritisation.

objectiveTo analyse the Cochrane Database of Systematic Reviews (CDSR) and determine whether systematic reviews and protocols accurately represent disease burden, as measured by disability-adjusted life years (DALYs) from the Global Burden of Disease (GBD) 2010 Study.

methodsTwo investigators collected GBD disability metrics for 12 external causes of injury in the GBD 2010 Study. These external causes were then assessed for systematic review and protocol representation in CDSR. Data was collected during the month of April 2015. There were no study participants aside from the researchers. Percentage of total 2010 DALYs, 2010 DALY rank, and median DALY percent change from 1990 to 2010 of the 12 external causes of injury were compared with CDSR representation of systematic reviews and protocols. Data were analysed for correlation using Spearman rank correlation.

resultsEleven of the 12 causes were represented by at least one systematic review or protocol in CDSR; the category collective violence and legal intervention had no representation in CDSR. Correlation testing revealed a strong positive correlation that was statistically significant. Representation of road injury; interpersonal violence; fire, heat, and hot substances; mechanical forces; poisonings, adverse effect of medical treatment, and animal contact was well aligned with respect to DALY. Representation of falls was greater compared to DALY, while self-harm, exposure to forces of nature, and other transport injury representation was lower compared to DALY. CONCLUSIONS AND RELEVANCE: CDSR representation of external causes of injury strongly correlates with disease burden. The number of systematic reviews and protocols was well aligned for seven out of 12 causes of injury. These results provide high-quality and transparent data that may guide future prioritisation decisions.

Indexed as

Databases, FactualResearchReview Literature as TopicCost of IllnessFemaleHumansMalePersons with DisabilitiesQuality-Adjusted Life YearsWounds and InjuriesBurden of diseaseCochraneDALYDisabilityEpidemiologyInjurySystematic reviewTrauma

Identifiers

PMID26804937
PMCPMC4862959
OpenAlexW2258493465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.