Trial reportClinical & experimental optometry2016
An analysis of observer-rated functional vision in patients implanted with the Argus II Retinal Prosthesis System at three years.
Trial report in Clinical & experimental optometry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Retinal Implantation of Electronic Vision Prostheses to Treat Retinitis Pigmentosa: A Systematic Review.Translational vision science & technology · 2021Pooled it
- A Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis: Interim Clinical Trial Results.Translational vision science & technology · 2021Trial
- Functional Vision in the Real-World Environment With a Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis.Translational vision science & technology · 2021Trial
- Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial.Ophthalmology · 2016Trial
- An analysis of observer-rated functional vision in patients implanted with the Argus II Retinal Prosthesis System at three years.Clinical & experimental optometry · 2016Trial
- Restorative and regenerative therapies for vision loss.Eye (London, England) · 2026Review
- Seeing anew: Mechanisms, outcomes, and challenges in adapting to restored sight via visual prostheses.Progress in retinal and eye research · 2026Review
- Gamification Enhances User Engagement and Task Performance in Prosthetic Vision Testing.Translational vision science & technology · 2026Article
- Gamification Enhances User Engagement and Task Performance in Prosthetic Vision Testing.medRxiv : the preprint server for health sciences · 2025Article
- Restoration of Sight with Electronic Retinal Prostheses.Annual review of vision science · 2025Review
- Optimizing electrical stimulation parameters to enhance visual cortex activation in retina degeneration rats.Scientific reports · 2025Article
- Static or Temporal? Semantic Scene Simplification to Aid Wayfinding in Immersive Simulations of Bionic Vision.Proceedings of the ACM Symposium on Virtual Reality Software and Technology. ACM Symposium on Virtual Reality Software and Technology · 2025Article
- Aligning Visual Prosthetic Development With Implantee Needs.Translational vision science & technology · 2024Article
- Aligning visual prosthetic development with implantee needs.medRxiv : the preprint server for health sciences · 2024Article
- Current Assistive Devices Usage and Recommendations for a Future Artificial Vision Prosthesis among Patients with Severe Visual Impairment Due to Inherited Retinal Diseases.Journal of clinical medicine · 2023Article
- Bioengineering strategies for restoring vision.Nature biomedical engineering · 2023Review
- Optimization and Validation of a Virtual Reality Orientation and Mobility Test for Inherited Retinal Degenerations.Translational vision science & technology · 2023Article
- Towards aJournal of neural engineering · 2022Article
- Current Modalities for Low Vision Rehabilitation.Cureus · 2021Review
- Effects of the Argus II Retinal Prosthesis System on the Quality of Life of Patients With Ultra-Low Vision Due to Retinitis Pigmentosa: Protocol for a Single-Arm, Mixed Methods Study.JMIR research protocols · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this analysis was to compare observer-rated tasks in patients implanted with the Argus II Retinal Prosthesis System, when the device is ON versus OFF.
methodsThe Functional Low-Vision Observer Rated Assessment (FLORA) instrument was administered to 26 blind patients implanted with the Argus II Retinal Prosthesis System at a mean follow-up of 36 months. FLORA is a multi-component instrument that consists in part of observer-rated assessment of 35 tasks completed with the device ON versus OFF. The ease with which a patient completes a task is scored using a four-point scale, ranging from easy (score of 1) to impossible (score of 4). The tasks are evaluated individually and organised into four discrete domains, including 'Visual orientation', 'Visual mobility', 'Daily life and 'Interaction with others'.
resultsTwenty-six patients completed each of the 35 tasks. Overall, 24 out of 35 tasks (69 per cent) were statistically significantly easier to achieve with the device ON versus OFF. In each of the four domains, patients' performances were significantly better (p < 0.05) with the device ON versus OFF, ranging from 19 to 38 per cent improvement.
conclusionPatients with an Argus II Retinal Prosthesis implanted for 18 to 44 months (mean 36 months), demonstrated significantly improved completion of vision-related tasks with the device ON versus OFF.
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