Evidence map›Paper›PMID 26804055›Full record

ArticleCNS neuroscience & therapeutics2016

Astroglial Activation and Tau Hyperphosphorylation Precede to Neuron Loss in a Neurodegenerative Mouse Model.

Jin-Xing Hou, Shan-Shan Cheng, Lu Chen, Qi-Hui Wang, Yun Shi, Yun Xu, Zhen-Yu Yin, Gui-Quan Chen

Abstract readLetter
In one paragraph

Article in CNS neuroscience & therapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Pen-2 Negatively Regulates the Differentiation of Oligodendrocyte Precursor Cells into Astrocytes in the Central Nervous System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  3. Article
  4. Article
  5. [BMC neurology · 2018
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jin-Xing HouState Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Shan-Shan ChengState Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Lu ChenState Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Qi-Hui WangState Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Yun ShiState Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.
Yun XuDepartment of Neurology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu Province, China.
Zhen-Yu YinDepartment of Geriatric, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu Province, China.
Gui-Quan ChenState Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Age FactorsAmyloid beta-Protein PrecursorAmyloid Precursor Protein SecretasesAnimalsAstrocytesDisease Models, AnimalGene Expression RegulationGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaGreen Fluorescent ProteinsMembrane GlycoproteinsMiceMice, TransgenicNeurodegenerative DiseasesNeuronsPhosphorylationAmyloid beta-Protein PrecursorAmyloid Precursor Protein SecretasesGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaGreen Fluorescent ProteinsMembrane Glycoproteinsnicastrin proteintau Proteins

Identifiers

PMID26804055
PMCPMC6492783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.