Evidence map›Paper›PMID 26803378›Full record

ArticleTrends in microbiology2016

HIV-1 Envelope Under Attack.

Wei Wei, Xiao-Fang Yu

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In one paragraph

Article in Trends in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Wei WeiFirst Hospital of Jilin University, Institute of Virology and AIDS Research, Changchun, Jilin Province, China; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
Xiao-Fang YuFirst Hospital of Jilin University, Institute of Virology and AIDS Research, Changchun, Jilin Province, China; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA. Electronic address: xyu2@jhu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human immunodeficiency virus type 1 (HIV-1) envelope (Env) plays a critical role in viral replication and represents a potential target for host antiviral factors. Recent work by Tada and colleagues identifies membrane-associated-RING-CH8 (MARCH8) as a potent anti-HIV factor blocking virion incorporation of Env. Thus, MARCH8 joins a growing list of host factors attacking HIV-1 Env.

Indexed as

env Gene Products, Human Immunodeficiency VirusHIV-1HIV InfectionsHumansMembrane GlycoproteinsUbiquitin-Protein LigasesViral Envelope ProteinsVirionenv Gene Products, Human Immunodeficiency VirusMembrane GlycoproteinsUbiquitin-Protein LigasesViral Envelope Proteinsenvelope glycoproteinHIV-1MARCH8virion incorporation

Identifiers

PMID26803378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.