Evidence map›Paper›PMID 26803211›Full record

ArticleEnvironmental research2016

Multimedia exposures to arsenic and lead for children near an inactive mine tailings and smelter site.

Miranda M Loh, Anastasia Sugeng, Nathan Lothrop, Walter Klimecki, Melissa Cox, Sarah T Wilkinson, Zhenqiang Lu, Paloma I Beamer

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  13. Seasonal Variation of Water Quality in Unregulated Domestic Wells.International journal of environmental research and public health · 2019
    Article
  14. Article
  15. Increasing Environmental Health Literacy through Contextual Learning in Communities at Risk.International journal of environmental research and public health · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Miranda M LohDepartment of Community, Environment and Policy, Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N. Martin Avenue, P.O. Box 245163, Tucson, AZ 85718, USA. Electronic address: mloh@email.arizona.edu.
Anastasia SugengDepartment of Community, Environment and Policy, Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N. Martin Avenue, P.O. Box 245163, Tucson, AZ 85718, USA.
Nathan LothropDepartment of Community, Environment and Policy, Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N. Martin Avenue, P.O. Box 245163, Tucson, AZ 85718, USA.
Walter KlimeckiDepartment of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, P.O. Box 210207, Tucson, AZ 85724, USA.
Melissa CoxHospital Medicine and Outreach, Department of Pediatrics, Diamond Children's Medical Center, The University of Arizona, 1501 N. Campbell Ave. Tucson, AZ 85724, USA.
Sarah T WilkinsonSuperfund Research Program, The University of Arizona, 1110 E. South Campus Dr., Tucson, AZ 85721, USA.
Zhenqiang LuBIO5 Institute, The University of Arizona, 1657 E. Mabel St., Tucson, AZ 85721, USA.
Paloma I BeamerDepartment of Community, Environment and Policy, Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N. Martin Avenue, P.O. Box 245163, Tucson, AZ 85718, USA.
University of Arizona · US

Funding

TRANSPORT OF TRACE METALS IN A POLLUTED AQUIFERP42ES004940 · NIEHS · UNIVERSITY OF ARIZONA · PI Xinxin Ding · 1990 to 2026
$68.1M
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
Relating Diesel Exhaust Exposure to Respiratory and Immune Outcomes in Early LifeK25HL103970 · NHLBI · UNIVERSITY OF ARIZONA · PI BEAMER, PALOMA I · 2011 to 2015
$666k
NHLBI NIH HHS K25 HL103970NIEHS NIH HHS P30 ES006694NIEHS NIH HHS P42 ES004940
6 · The paper itself

Abstract

Children living near contaminated mining waste areas may have high exposures to metals from the environment. This study investigates whether exposure to arsenic and lead is higher in children in a community near a legacy mine and smelter site in Arizona compared to children in other parts of the United States and the relationship of that exposure to the site. Arsenic and lead were measured in residential soil, house dust, tap water, urine, and toenail samples from 70 children in 34 households up to 7 miles from the site. Soil and house dust were sieved, digested, and analyzed via ICP-MS. Tap water and urine were analyzed without digestion, while toenails were washed, digested and analyzed. Blood lead was analyzed by an independent, certified laboratory. Spearman correlation coefficients were calculated between each environmental media and urine and toenails for arsenic and lead. Geometric mean arsenic (standard deviation) concentrations for each matrix were: 22.1 (2.59) ppm and 12.4 (2.27)ppm for soil and house dust (<63μm), 5.71 (6.55)ppb for tap water, 14.0 (2.01)μg/L for specific gravity-corrected total urinary arsenic, 0.543 (3.22)ppm for toenails. Soil and vacuumed dust lead concentrations were 16.9 (2.03)ppm and 21.6 (1.90) ppm. The majority of blood lead levels were below the limit of quantification. Arsenic and lead concentrations in soil and house dust decreased with distance from the site. Concentrations in soil, house dust, tap water, along with floor dust loading were significantly associated with toenail and urinary arsenic but not lead. Mixed models showed that soil and tap water best predicted urinary arsenic. In our study, despite being present in mine tailings at similar levels, internal lead exposure was not high, but arsenic exposure was of concern, particularly from soil and tap water. Naturally occurring sources may be an additional important contributor to exposures in certain legacy mining areas.

Indexed as

Environmental ExposureArizonaArsenicChildChild, PreschoolDustFemaleHumansInfantLeadMaleMiningNailsSoil PollutantsArsenicDustLeadSoil PollutantsBiomarkersExposure assessmentHazardous wasteMetalsMultimedia

Identifiers

PMID26803211
PMCPMC5344033
OpenAlexW2275866684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.