ArticleCerebral cortex (New York, N.Y. : 1991)2016
Monaural Congenital Deafness Affects Aural Dominance and Degrades Binaural Processing.
Article in Cerebral cortex (New York, N.Y. : 1991), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 104 citations in OpenAlex.
- Effects of Cochlear Implantation on Binaural Hearing in Adults With Unilateral Hearing Loss.Trends in hearingTrial
- A tale of two ears: development of binaural auditory processing in the big brown bat.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Neurophysiological sensitivity to envelope and pulse timing interaural time differences in cochlear implanted rats with different hearing experiences.The Journal of physiology · 2026Article
- Spatial hearing adaptation in congenital and acquired single-sided deafness.Frontiers in neuroscience · 2026Article
- Hearing Outcomes in Children with Unilateral Hearing Loss. The Benefits of Rehabilitative Strategies: Preliminary Results.Audiology research · 2025Article
- Dissociated Representation of Binaural Cues in Single-Sided Deafness: Implications for Cochlear Implantation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Multidimensional Alternating Kernel Method for cortical layer segmentation in 3D reconstructed histology.MethodsX · 2024Article
- Bidirectional remodeling of the central auditory system caused by unilateral auditory deprivation.Frontiers in neurology · 2024Review
- Interaural time difference sensitivity under binaural cochlear implant stimulation persists at high pulse rates up to 900 pps.Scientific reports · 2023Article
- A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant.Scientific reports · 2023Article
- Auditory cortical plasticity after cochlear implantation in asymmetric hearing loss is related to spatial hearing: a PET H215O study.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Cochlear implantation in unilateral hearing loss: impact of short- to medium-term auditory deprivation.Frontiers in neuroscience · 2023Article
- Cortical imbalance following delayed restoration of bilateral hearing in deaf adolescents.Human brain mapping · 2022Article
- Functional Reorganization of the Central Auditory System in Children with Single-Sided Deafness: A Protocol Using fNIRS.Brain sciences · 2022Article
- Characteristics of sound localization in children with unilateral microtia and atresia and predictors of localization improvement when using a bone conduction device.Frontiers in neuroscience · 2022Article
- Deficient Recurrent Cortical Processing in Congenital Deafness.Frontiers in systems neuroscience · 2022Article
- Dichotic listening performance with cochlear-implant simulations of ear asymmetry is consistent with difficulty ignoring clearer speech.Attention, perception & psychophysics · 2021Article
- Changes in the Gene Expression Profiles of the Inferior Colliculus Following Unilateral Cochlear Ablation in Adult Rats.Biochemical genetics · 2021Article
- Microsecond interaural time difference discrimination restored by cochlear implants after neonatal deafness.eLife · 2021Article
- Ear-Specific Hemispheric Asymmetry in Unilateral Deafness Revealed by Auditory Cortical Activity.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cortical development extensively depends on sensory experience. Effects of congenital monaural and binaural deafness on cortical aural dominance and representation of binaural cues were investigated in the present study. We used an animal model that precisely mimics the clinical scenario of unilateral cochlear implantation in an individual with single-sided congenital deafness. Multiunit responses in cortical field A1 to cochlear implant stimulation were studied in normal-hearing cats, bilaterally congenitally deaf cats (CDCs), and unilaterally deaf cats (uCDCs). Binaural deafness reduced cortical responsiveness and decreased response thresholds and dynamic range. In contrast to CDCs, in uCDCs, cortical responsiveness was not reduced, but hemispheric-specific reorganization of aural dominance and binaural interactions were observed. Deafness led to a substantial drop in binaural facilitation in CDCs and uCDCs, demonstrating the inevitable role of experience for a binaural benefit. Sensitivity to interaural time differences was more reduced in uCDCs than in CDCs, particularly at the hemisphere ipsilateral to the hearing ear. Compared with binaural deafness, unilateral hearing prevented nonspecific reduction in cortical responsiveness, but extensively reorganized aural dominance and binaural responses. The deaf ear remained coupled with the cortex in uCDCs, demonstrating a significant difference to deprivation amblyopia in the visual system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.