Evidence map›Paper›PMID 26802775›Full record

ReviewJournal of the American Academy of Child and Adolescent Psychiatry2016

The National Institute of Mental Health Research Domain Criteria and Clinical Research in Child and Adolescent Psychiatry.

Marjorie Garvey, Shelli Avenevoli, Kathleen Anderson

Abstract readReview
In one paragraph

Review in Journal of the American Academy of Child and Adolescent Psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 93 citations in OpenAlex.

  1. Trial
  2. Trial
  3. The Research Domain Criteria (RDoC) and Youth Depression - In Context.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2026
    Article
  4. Article
  5. Article
  6. Machine Learning Differentiation of Autism Spectrum Sub-Classifications.Journal of autism and developmental disorders · 2024
    Article
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  8. Article
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  12. Article
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  15. Review
  16. Article
  17. Article
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  19. Article
  20. Phenoscreening: a developmental approach to research domain criteria-motivated sampling.Journal of child psychology and psychiatry, and allied disciplines · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marjorie GarveyDivision of Translational Research, National Institute of Mental Health (NIMH), Bethesda, MD. Electronic address: marjorie.garvey@nih.gov.
Shelli AvenevoliDivision of Translational Research, National Institute of Mental Health (NIMH), Bethesda, MD.
Kathleen AndersonDivision of Translational Research, National Institute of Mental Health (NIMH), Bethesda, MD.
National Institute of Mental Health · US

Funding

Intramural NIH HHS Z99 MH999999
6 · The paper itself

Abstract

objectiveThis review discusses the relevance of the National Institute of Mental Health (NIMH) Research Domain Criteria (RDoC) to clinical research in child and adolescent psychiatry.

methodWe summarize the characteristics of the NIMH RDoC project and then provide examples of RDoC designs that are of relevance to clinical investigators in child and adolescent psychiatry. The final section addresses questions regarding the impact of RDoC on clinical care.

resultsRDoC encourages investigators to investigate psychopathology dimensionally: greater or lesser degrees of healthy/adapted functioning of neurobiological, cognitive, and behavioral processes (constructs) that cut across current diagnostic categories. Elucidation of the developmental components of RDoC constructs is needed to ensure they are fully validated. Integrating RDoC approaches into clinical research of child and adolescent psychopathology is contributing to our understanding of development as an aspect of the heterogeneity within DSM disorders and commonalities across seemingly disparate disorders. Continued efforts promise to also explain the processes that lead to mental illness in at-risk populations.

conclusionIncorporating an RDoC approach in clinical research in child and adolescent psychiatry promises to be a fruitful avenue of research into the root causes and manifestations of mental illness, which will eventually lead to more precise treatments. Although the long-term aspiration of RDoC is to help reduce the burden of suffering for those with mental illnesses, it is not intended to be used for practical clinical purposes at this early stage.

Indexed as

AdolescentAdolescent PsychiatryChildChild PsychiatryDiagnostic and Statistical Manual of Mental DisordersHumansMental DisordersNational Institute of Mental Health (U.S.)PsychiatryPsychopathologyUnited Stateschild and adolescent psychiatryclinical researchNational Institute of Mental HealthRDoCResearch Domain Criteria

Identifiers

PMID26802775
PMCPMC4724376
OpenAlexW2197939624

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.