ArticlePsychoneuroendocrinology2016
Hormone levels in neonatal hair reflect prior maternal stress exposure during pregnancy.
Article in Psychoneuroendocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A systematic review of studies utilizing hair glucocorticoids as a measure of stress suggests the marker is more appropriate for quantifying short-term stressors.Scientific reports · 2019Pooled it
- Parental Incarceration, Attachment to Caregivers, and Young Children's Physiological Stress.Developmental psychobiology · 2025Article
- Echoes of conflict and displacement in maternal health: Life-course violence, timing, and maternal stress after childbirth at the northern Thailand-Myanmar border.Psychoneuroendocrinology · 2025Article
- Higher prenatal anxiety predicts lower neonatal hair cortisol.Psychoneuroendocrinology · 2024Article
- Prolonged Physiological Stress Is Associated With a Lower Rate of Exploratory Learning That Is Compounded by Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Getting under the skin: Physiological stress and witnessing paternal arrest in young children with incarcerated fathers.Developmental psychobiology · 2021Article
- Perinatal determinants of neonatal hair glucocorticoid concentrations.Psychoneuroendocrinology · 2021Article
- Within-person changes of cortisol, dehydroepiandrosterone, testosterone, estradiol, and progesterone in hair across pregnancy, with comparison to a non-pregnant reference group.Comprehensive psychoneuroendocrinology · 2021Article
- Prenatal maternal stress and child hair cortisol four years later: Evidence from a low-income sample.Psychoneuroendocrinology · 2020Article
- Maternal and Neonatal Hair Cortisol Levels Are Associated with Infant Neurodevelopment at Six Months of Age.Journal of clinical medicine · 2019Article
- Parental habituation to human disturbance over time reduces fear of humans in coyote offspring.Ecology and evolution · 2018Article
- Radiolabel validation of cortisol in the hair of rhesus monkeys.Psychoneuroendocrinology · 2018Article
- Maternal Stress During Pregnancy Is Associated with Decreased Cortisol and Cortisone Levels in Neonatal Hair.Hormone research in paediatrics · 2018Article
- Newborn infants' hair cortisol levels reflect chronic maternal stress during pregnancy.PloS one · 2018Article
- A longitudinal study of hair cortisol concentrations in Macaca nemestrina mothers and infants.American journal of primatology · 2017Article
- The quantification of reproductive hormones in the hair of captive adult brown bears and their application as indicators of sex and reproductive state.Conservation physiology · 2017Article
- Gestational Timing of Prenatal Disturbance and Fetal Sex Determine the Developmental Outcomes.Neonatology · 2016Article
- Amniotic fluid cortisol predicts neonatal and infant development in non-stressed rhesus monkeys: Implications for prenatal stress.Neurotoxicology and teratologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Hormones present in hair provide summative information about endocrine activity while the hair was growing. Therefore, it can be collected from an infant after birth and still provide retrospective information about hormone exposure during prenatal development. We employed this approach to determine whether a delimited period of maternal stress during pregnancy affected the concentrations of glucocorticoids and gonadal hormones in the hair of neonatal rhesus monkeys. Hair from 22 infant monkeys exposed to 5 weeks of gestational disturbance was compared to specimens from 13 infants from undisturbed control pregnancies. Using an LC/MS/MS based technique, which permitted seven steroid hormones to be quantified simultaneously, we found 2 hormones were significantly different in infants from disturbed pregnancies. Cortisol and testosterone levels were lower in the hair of both male and female neonates. Maternal hair hormone levels collected on the same day after delivery no longer showed effects of the disturbance earlier during pregnancy. This study documents that a period of acute stress, lasting for 20% of gestation, has sustained effects on the hormones to which a developing fetus is exposed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.