Evidence map›Paper›PMID 26802287›Full record

ReviewCurrent opinion in immunology2016

Development of invariant natural killer T cells.

Laurent Gapin

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed.

  1. Trial
  2. Review
  3. Metabolic control of innate-like T cells.Nature reviews. Immunology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. T Cell Development: From T-Lineage Specification to Intrathymic Maturation.Advances in experimental medicine and biology · 2025
    Review
  9. Review
  10. Article
  11. IL-27 regulates the differentiation of follicular helper NKT cells via metabolic adaptation of mitochondria.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. A guide to thymic selection of T cells.Nature reviews. Immunology · 2024
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. MAIT cells and the microbiome.Frontiers in immunology · 2023
    Review
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Laurent GapinDepartment of Immunology and Microbiology, University of Colorado Anschutz Medical campus and National Jewish Health, Aurora, CO 80045, USA. Electronic address: Laurent.gapin@ucdenver.edu.

Funding

iNKT Cell Recognition of Endogenous Lipid AntigensR01AI092108 · NIAID · UNIVERSITY OF COLORADO DENVER · PI GAPIN, LAURENT · 2011 to 2014
$1.5M
NIAID NIH HHS AI092108NIAID NIH HHS R01 AI092108
6 · The paper itself

Abstract

Invariant natural killer T (iNKT) cells develop into functionally distinct subsets. Each subset expresses a unique combination of transcription factors that regulate cytokine gene transcription upon activation. The tissue distribution and localization within tissues also varies between subsets. Importantly, the relative abundance of the various subsets is directly responsible for altering several immunological parameters, which subsequently affect the immune response. Here, I review recent advances in our understanding of the molecular regulation of iNKT cell subset development.

Indexed as

AnimalsHumansLymphocyte ActivationNatural Killer T-CellsThymus GlandTissue DistributionT-Lymphocyte SubsetsTranscription FactorsTranscription Factors

Identifiers

PMID26802287
PMCPMC4801673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.