Evidence map›Paper›PMID 26801662›Full record

ArticleJournal of medical ultrasonics (2001)2016

Impact of parametric imaging on contrast-enhanced ultrasound of breast cancer.

Aya Noro, Takashi Nakamura, Toshiko Hirai, Masayo Haga, Toyoki Kobayashi, Akinobu Hayashi, Yuji Kozuka, Tokiko Nakai, Toru Ogura, Tomoko Ogawa

Abstract readEvaluation StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of medical ultrasonics (2001), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Arrival-Time Parametric Imaging in Contrast-Enhanced Ultrasound for Thyroid Nodule Differentiation.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  2. Enhanced Diagnostic Imaging: Arrival-Time Parametric Imaging in Contrast-Enhanced Ultrasound for Multi-Organ Assessment.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aya NoroDepartment of Breast Surgery, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. xxxme_heavenly@yahoo.co.jp.
Takashi NakamuraDepartment of Breast Surgery, Nabari City Hospital, Nabari, Mie, Japan.
Toshiko HiraiDepartment of Endoscopy and Ultrasound, Nara Medical University Hospital, Kashihara, Nara, Japan.
Masayo HagaDepartment of Radiology, Nara Medical University Hospital, Kashihara, Nara, Japan.
Toyoki KobayashiDepartment of Breast Surgery, Nara Medical University Hospital, Kashihara, Nara, Japan.
Akinobu HayashiDepartment of Pathology, Mie University Hospital, Tsu, Mie, Japan.
Yuji KozukaDepartment of Pathology, Mie University Hospital, Tsu, Mie, Japan.
Tokiko NakaiDepartment of Pathology, Nara Medical University Hospital, Kashihara, Nara, Japan.
Toru OguraCenter of Development of Clinical Study, Mie University Hospital, Tsu, Mie, Japan.
Tomoko OgawaDepartment of Breast Surgery, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo prospectively evaluate the usefulness of contrast-enhanced ultrasound (CEUS) using parametric imaging for breast cancer in a multicenter study.

methodsA total of 65 patients with breast cancer were included in this study. CEUS was performed, and still images on peak time (S), accumulated images (A) and parametric images (P) were generated from the raw data. Four blind reviewers ranked the best visible images as first place, and determined second and third place consecutively. We compared the average ranking of each image. The maximal diameter of the tumor determined on ultrasonography and MRI was compared with the corresponding pathological maximal diameter for 48 of the 65 patients. The correlation between the diameter determined by two experts and two beginners was analyzed.

resultsThe average rank of visibility was as follows: P, 1.44; A, 2.04; and S, 2.52. The correlation between each image and the pathology was as follows: P, r = 0.664; A, r = 0.630; S, r = 0.717; and MRI, r = 0.936. There were no significant differences among the correlation between the experts and beginners in each image.

conclusionsThe use of parametric imaging improves the visibility of CEUS. The maximal diameter of the tumor determined on CEUS correlates substantially with the pathology.

Indexed as

Contrast MediaFerric CompoundsIronOxidesAdultAgedAged, 80 and overBreast NeoplasmsCarcinomaFemaleHumansMagnetic Resonance ImagingMiddle AgedObserver VariationProspective StudiesSingle-Blind MethodContrast MediaFerric CompoundsIronOxidesSonazoidBreast cancerContrast-enhanced ultrasoundParametric imageSonazoid®Visibility

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.