Evidence map›Paper›PMID 26801236›Full record

ArticleJournal of neuroengineering and rehabilitation2016

A statistical analysis of cervical auscultation signals from adults with unsafe airway protection.

Joshua M Dudik, Atsuko Kurosu, James L Coyle, Ervin Sejdić

Registry-linked trialAbstract read
In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04468191 (Quantifying Fatigue of the Respiratory and Swallowing Musculature in Patients With Amyotrophic Lateral Sclerosis), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04468191 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

Quantifying Fatigue of the Respiratory and Swallowing Musculature in Patients With Amyotrophic Lateral Sclerosis

TypeinterventionalSponsorCara DonohueRan2021 to 2021Enrolled0ConditionsAmyotrophic Lateral Sclerosis, Dysphagia, Dyspnea, Respiration DisordersArmsExperimental expiratory muscle strength training (EMST), Sham expiratory muscle strength training (EMST)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joshua M DudikDepartment of Electrical and Computer Engineering, Swanson School of Engineering, University of Pittsburgh, 3700 O'Hara Street, Pittsburgh, PA, 15261, USA. jmd151@pitt.edu.
Atsuko KurosuDepartment of Communication Science and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh, 4028 Forbes Tower, Pittsburgh, PA, 15260, USA. atk22@pitt.edu.
James L CoyleDepartment of Communication Science and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh, 4028 Forbes Tower, Pittsburgh, PA, 15260, USA. jcoyle@pitt.edu.
Ervin SejdićDepartment of Electrical and Computer Engineering, Swanson School of Engineering, University of Pittsburgh, 3700 O'Hara Street, Pittsburgh, PA, 15261, USA. esejdic@ieee.org.

Funding

The Aspirometer: A noninvasive tool to detect swallowing safety and efficiencyR01HD074819 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COYLE, JAMES L, SEJDIC, ERVIN · 2013 to 2022
$3.0M
NICHD NIH HHS R01 HD074819NICHD NIH HHS R01HD074819
6 · The paper itself

Abstract

backgroundAspiration, where food or liquid is allowed to enter the larynx during a swallow, is recognized as the most clinically salient feature of oropharyngeal dysphagia. This event can lead to short-term harm via airway obstruction or more long-term effects such as pneumonia. In order to non-invasively identify this event using high resolution cervical auscultation there is a need to characterize cervical auscultation signals from subjects with dysphagia who aspirate.

methodsIn this study, we collected swallowing sound and vibration data from 76 adults (50 men, 26 women, mean age 62) who underwent a routine videofluoroscopy swallowing examination. The analysis was limited to swallows of liquid with either thin (<5 cps) or viscous (≈300 cps) consistency and was divided into those with deep laryngeal penetration or aspiration (unsafe airway protection), and those with either shallow or no laryngeal penetration (safe airway protection), using a standardized scale. After calculating a selection of time, frequency, and time-frequency features for each swallow, the safe and unsafe categories were compared using Wilcoxon rank-sum statistical tests.

resultsOur analysis found that few of our chosen features varied in magnitude between safe and unsafe swallows with thin swallows demonstrating no statistical variation. We also supported our past findings with regard to the effects of sex and the presence or absence of stroke on cervical ausculation signals, but noticed certain discrepancies with regards to bolus viscosity.

conclusionsOverall, our results support the necessity of using multiple statistical features concurrently to identify laryngeal penetration of swallowed boluses in future work with high resolution cervical auscultation.

Indexed as

DeglutitionAccelerometryAlgorithmsAuscultationCervical VertebraeDeglutition DisordersFemaleFluoroscopyHumansLarynxMaleMiddle AgedPneumonia, AspirationSignal Processing, Computer-AssistedVibration

Identifiers

PMID26801236
PMCPMC4722771

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.