Observational studyWorld journal of surgical oncology2016
Total thyroidectomy as primary surgical management for thyroid disease: surgical therapy experience from 5559 thyroidectomies in a less-developed region.
Observational study in World journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- A Meta-Analysis of Risk Factors for Transient and Permanent Hypocalcemia After Total Thyroidectomy.Frontiers in oncology · 2020Pooled it
- Intraoperative Nerve Monitoring Parameters and Risk of Recurrent Laryngeal Nerve Injury in Thyroidectomy: A Systematic Review and Meta-Analysis.Biomedicines · 2025Review
- Hyperthyroidism with a normal cervical thyroid gland: A rare case report of thyroid hormone releasing mass in the chest.International journal of surgery case reports · 2025Article
- Unilateral right thyroid swelling with contralateral left mediastinal mass of benign ectopic thyroid tissue: a rare case report.Annals of medicine and surgery (2012) · 2025Article
- The mammalian acid chitinase promotes oncogenic properties of thyroid cancer cells through the JAK2/STAT3 pathway.European thyroid journal · 2025Article
- Celastrol promotes apoptotic cell death in thyroid cancer cells through a caspases-dependent pathway.Thyroid research · 2025Article
- Thyroidectomy and Its Complications: A Comprehensive Analysis.Biomedicines · 2025Article
- Postoperative complications and long-term outcomes after total and subtotal thyroidectomy: a retrospective study.Scientific reports · 2025Article
- The clinicopathological landscape of thyroid cancer in South Africa-A multi-institutional review.World journal of surgery · 2024Article
- Circ_0003747 promotes thyroid cancer progression by sponging miR-338-3p to upregulate PLCD3 expression.Epigenetics · 2023Article
- The prevalence of hypocalcemia following total thyroidectomy. A retrospective study based at King Abdulaziz University Hospital, Jeddah, Saudi Arabia.Saudi medical journal · 2020Article
- Efficacy and safety of LigaSure™ small jaw instrument in thyroidectomy: a 1-year prospective observational study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Observational
- Population-Based Assessment of Complications Following Surgery for Thyroid Cancer.The Journal of clinical endocrinology and metabolism · 2017Article
- Parathyroid Autotransplantation During Thyroid Surgery: A Novel Technique Using a Cell Culture Nutrient Solution.World journal of surgery · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to evaluate the safety of total thyroidectomy for thyroid disorders and summarise the treatment experience in a less-developed region.
methodsThis was a retrospective observational cohort study using the computerised database of the First Affiliated Hospital of Harbin Medical University. All consecutive thyroidectomy patients from 2003 to 2014 were included in this study. Demographics, surgical procedure, diagnoses, morbidity and mortality were retrospectively reviewed.
resultsThere were a total of 714 men and 4845 women in this study, with a mean age of 55 (range 9-87) years. A total of 4632 patients underwent total thyroidectomy for primary surgical treatment, and 189 patients previously underwent partial thyroidectomy. A total of 56.2% of the patients had multinodular goitre, including 12.23% who were thyrotoxic. Graves' disease and Hashimoto's disease were diagnosed in 2.82 and 7.23% of the patients, respectively. Papillary thyroid cancer was identified in 1336 patients, 44.99% of whom had papillary microcarcinoma. The total prevalence of permanent complications of first-time and secondary surgeries was 0.35 and 7.41%, respectively. During thyroid surgery, 945 patients underwent parathyroid autotransplantation.
conclusionsInitial total thyroidectomy can be safely performed for both benign and malignant thyroid diseases in a less-developed region. The morbidity of a secondary surgical procedure after subtotal thyroidectomy is significantly high compared to first-time surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.