Evidence map›Paper›PMID 26801206›Full record

ReviewPlant biotechnology journal2016

Metabolic regulation of triacylglycerol accumulation in the green algae: identification of potential targets for engineering to improve oil yield.

Elton C Goncalves, Ann C Wilkie, Matias Kirst, Bala Rathinasabapathi

Open access · goldAbstract readReview
In one paragraph

Review in Plant biotechnology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 220 citations in OpenAlex.

  1. RSC advances · 2026
    Article
  2. iScience · 2026
    Review
  3. Harnessing microalgae for bioproducts: innovations in synthetic biology.World journal of microbiology & biotechnology · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Ectopic Expression ofPlants (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Review
  13. Frontiers in plant science · 2023
    Article
  14. COPlants (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elton C GoncalvesPlant Molecular and Cellular Biology Program, Horticultural Sciences Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA.
Ann C WilkieSoil and Water Science Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA.
Matias KirstSchool of Forestry, University of Florida, Gainesville, FL, USA.
Bala RathinasabapathiPlant Molecular and Cellular Biology Program, Horticultural Sciences Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, USA.
University of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The great need for more sustainable alternatives to fossil fuels has increased our research interests in algal biofuels. Microalgal cells, characterized by high photosynthetic efficiency and rapid cell division, are an excellent source of neutral lipids as potential fuel stocks. Various stress factors, especially nutrient-starvation conditions, induce an increased formation of lipid bodies filled with triacylglycerol in these cells. Here we review our knowledge base on glycerolipid synthesis in the green algae with an emphasis on recent studies on carbon flux, redistribution of lipids under nutrient-limiting conditions and its regulation. We discuss the contributions and limitations of classical and novel approaches used to elucidate the algal triacylglycerol biosynthetic pathway and its regulatory network in green algae. Also discussed are gaps in knowledge and suggestions for much needed research both on the biology of triacylglycerol accumulation and possible avenues to engineer improved algal strains.

Indexed as

BiofuelsCarbonChlorophytaGenetic EngineeringLipid DropletsMetabolic EngineeringMicroalgaeNitrogenRegulonStarchTriglyceridesBiofuelsCarbonNitrogenStarchTriglyceridesacyltransferasesalgaebiofuelfatty acidslipidlipid dropletsnutrient starvationtranscription factorstriacylglycerol

Identifiers

PMID26801206
PMCPMC5066758
OpenAlexW2254578977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.