ArticlePloS one2016
Spectral Sensitivity Measured with Electroretinogram Using a Constant Response Method.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Accessible and robust machine learning approaches to improve the opsin genotype-phenotype map.Molecular biology and evolution · 2026Article
- Red Light Sensitivity of Non-image and Image Forming Visual Systems of Laboratory Rodents: Circadian Disruption and Behavioral Detection.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Far-red LED light alters circadian rhythms and elicits dark-adapted ERG responses in rodents.PloS one · 2025Article
- Relative importance of intensity and spectrum of artificial light at night in disrupting behavior of a nocturnal rodent.The Journal of experimental biology · 2024Article
- The Future Is Not Bright: Evaluation of Rat Preferences for Color and Intensity of Light.Animals : an open access journal from MDPI · 2024Article
- Discovering genotype-phenotype relationships with machine learning and the Visual Physiology Opsin Database (VPOD).GigaScience · 2024Article
- Reproducible and fully automated testing of nocifensive behavior in mice.Cell reports methods · 2023Article
- Extensive topographic remapping and functional sharpening in the adult rat visual pathway upon first visual experience.PLoS biology · 2023Article
- Effects of light therapy on sleep/wakefulness, daily rhythms, and the central orexin system in a diurnal rodent model of seasonal affective disorder.Journal of affective disorders · 2023Article
- Ethorobotic rats for rodent behavioral research: design considerations.Frontiers in behavioral neuroscience · 2023Article
- Effects of bright light therapy on neuroinflammatory and neuroplasticity markers in a diurnal rodent model of Seasonal Affective Disorder.Annals of medicine · 2023Article
- Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model.Nature communications · 2022Article
- Circadian Sensitivity of Noise Trauma-Induced Hearing Loss and Tinnitus in Mongolian Gerbils.Frontiers in neuroscience · 2022Article
- The Impact of the Spectral Radiation Environment on the Maximum Absorption Wavelengths of Human Vision and Other Species.Life (Basel, Switzerland) · 2021Article
- Reply to: Questions about the role of P3HT nanoparticles in retinal stimulation.Nature nanotechnology · 2021Article
- Green Light Antinociceptive and Reversal of Thermal and Mechanical Hypersensitivity Effects Rely on Endogenous Opioid System Stimulation.The journal of pain · 2021Article
- Article
- Automated methods for efficient and accurate electroretinography.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021Article
- Challenging a Myth and Misconception: Red-Light Vision in Rats.Animals : an open access journal from MDPI · 2020Article
- Short-Wavelength (Violet) Light Protects Mice From Myopia Through Cone Signaling.Investigative ophthalmology & visual science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new method is presented to determine the retinal spectral sensitivity function S(λ) using the electroretinogram (ERG). S(λ)s were assessed in three different species of myomorph rodents, Gerbils (Meriones unguiculatus), Wistar rats (Ratus norvegicus), and mice (Mus musculus). The method, called AC Constant Method, is based on a computerized automatic feedback system that adjusts light intensity to maintain a constant-response amplitude to a flickering stimulus throughout the spectrum, as it is scanned from 300 to 700 nm, and back. The results are presented as the reciprocal of the intensity at each wavelength required to maintain a constant peak to peak response amplitude. The resulting S(λ) had two peaks in all three rodent species, corresponding to ultraviolet and M cones, respectively: 359 nm and 511 nm for mice, 362 nm and 493 nm for gerbils, and 362 nm and 502 nm for rats. Results for mouse and gerbil were similar to literature reports of S(λ) functions obtained with other methods, confirming that the ERG associated to the AC Constant-Response Method was effective to obtain reliable S(λ) functions. In addition, due to its fast data collection time, the AC Constant Response Method has the advantage of keeping the eye in a constant light adapted state.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.