Evidence map›Paper›PMID 26799810›Full record

ArticleThe Science of the total environment2016

Planning for climate change: The need for mechanistic systems-based approaches to study climate change impacts on diarrheal diseases.

Jonathan E Mellor, Karen Levy, Julie Zimmerman, Mark Elliott, Jamie Bartram, Elizabeth Carlton, Thomas Clasen, Rebecca Dillingham, Joseph Eisenberg, Richard Guerrant and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Science of the total environment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Modeling environmentally mediated rotavirus transmission: The role of temperature and hydrologic factors.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Pooled it
  2. Pooled it
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  9. Review
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  12. Uncovering social and environmental factors that increase the burden of climate-sensitive diarrheal infections on children.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
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  16. Review
  17. Article
  18. Heavy Rainfall Events and Diarrheal Diseases: The Role of Urban-Rural Geography.The American journal of tropical medicine and hygiene · 2020
    Article
  19. Sanitation for Low-Income Regions: A Cross-Disciplinary Review.Annual review of environment and resources · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 1 country.

Jonathan E MellorDepartment of Civil and Environmental Engineering, University of Connecticut, 261 Glenbrook Road, Storrs, CT 06269-3037, USA. Electronic address: mellor@engineer.uconn.edu.
Karen LevyDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Julie ZimmermanDepartment of Chemical and Environmental Engineering, School of Engineering & Applied Science, Yale University, New Haven, CT, USA.
Mark ElliottDepartment of Civil, Construction and Environmental Engineering, The College of Engineering, University of Alabama, Tuscaloosa, AL, USA.
Jamie BartramWater Institute, Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Elizabeth CarltonDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado at Denver, Aurora, CO, USA.
Thomas ClasenDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Rebecca DillinghamThe Center for Global Health, University of Virginia, Charlottesville, VA, USA.
Joseph EisenbergSchool of Public Health, University of Michigan, Ann Arbor, MI, USA.
Richard GuerrantThe Center for Global Health, University of Virginia, Charlottesville, VA, USA.
Daniele LantagneDepartment of Civil and Environmental Engineering, School of Engineering, Tufts University, Medford, MA, USA.
James MihelcicDepartment of Civil and Environmental Engineering, The College of Engineering, University of South Florida, Tampa, FL, USA.
Kara NelsonDepartment of Civil and Environmental Engineering, University of California, Berkeley, CA, USA.
Center for Global Health · USEmory University · USColorado School of Public Health · USTufts University · USUniversity of Alabama · USUniversity of California, Berkeley · USUniversity of Connecticut · USUniversity of Michigan · USUniversity of North Carolina at Chapel Hill · USUniversity of South Florida · USYale University · US

Funding

Impacts of Human Movement on Regional Strain Distribution of Diarrheagenic E.coliK01AI103544 · NIAID · EMORY UNIVERSITY · PI LEVY, KAREN · 2013 to 2017
$655k
Social Vulnerability and Climatic Drivers of Enteric Disease in Rural EcuadorR21TW009032 · FIC · EMORY UNIVERSITY · PI LEVY, KAREN · 2011 to 2011
$246k
FIC NIH HHS R21 TW009032NIAID NIH HHS K01 AI103544
6 · The paper itself

Abstract

Increased precipitation and temperature variability as well as extreme events related to climate change are predicted to affect the availability and quality of water globally. Already heavily burdened with diarrheal diseases due to poor access to water, sanitation and hygiene facilities, communities throughout the developing world lack the adaptive capacity to sufficiently respond to the additional adversity caused by climate change. Studies suggest that diarrhea rates are positively correlated with increased temperature, and show a complex relationship with precipitation. Although climate change will likely increase rates of diarrheal diseases on average, there is a poor mechanistic understanding of the underlying disease transmission processes and substantial uncertainty surrounding current estimates. This makes it difficult to recommend appropriate adaptation strategies. We review the relevant climate-related mechanisms behind transmission of diarrheal disease pathogens and argue that systems-based mechanistic approaches incorporating human, engineered and environmental components are urgently needed. We then review successful systems-based approaches used in other environmental health fields and detail one modeling framework to predict climate change impacts on diarrheal diseases and design adaptation strategies.

Indexed as

Climate ChangeSystems AnalysisDiarrheaEnvironmental HealthHumansSanitationClimate changeComplex systemsCoupled systemsDiarrheaHealthWater

Identifiers

PMID26799810
PMCPMC4818006
OpenAlexW2288581010

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.